62956-62-1

Basic information

• Product Name: 6-METHOXYINDANE-1-CARBOXYLIC ACID
• Synonyms: 6-METHOXYINDANE-1-CARBOXYLIC ACID;6-methoxy-2,3-dihydro-1H-indene-1-carboxylic acid
• CAS NO: 62956-62-1
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Mol File: 62956-62-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 357.5°C at 760 mmHg
• Flash Point: 143.2°C
• Appearance: /
• Density: 1.241g/cm³
• Vapor Pressure: 9.85E-06mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly, Sonicated)
• CAS DataBase Reference: 6-METHOXYINDANE-1-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHOXYINDANE-1-CARBOXYLIC ACID(62956-62-1)
• EPA Substance Registry System: 6-METHOXYINDANE-1-CARBOXYLIC ACID(62956-62-1)

Safety Data

• Hazardous Substances Data: 62956-62-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H12O3/c1-14-8-4-2-7-3-5-9(11(12)13)10(7)6-8/h2,4,6,9H,3,5H2,1H3,(H,12,13)

Upstream product

• 68549-22-4 6-methoxy-2,3-dihydro-1H-indene-1-carbonitrile 
• 15378-02-6 3-(3-Methoxyphenyl)succinic acid 
• 17825-44-4 3-Carboxy-5-methoxy-indanon 
• 134111-82-3 1-(1,3-dithian-2-yl)-6-methoxy-2,3-dihydro-1H-inden-1-ol 
• 13623-25-1 6-methoxy-2,3-dihydro-1H-inden-1-one 
• 134111-83-4 2-(6-methoxy-2,3-dihydro-1H-inden-1-ylidene)-1,3-dithiane 

Downstream Products

• 68549-22-4 6-methoxy-2,3-dihydro-1H-indene-1-carbonitrile 

Relevant articles and documents

DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS

Compounds of formula I: I are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.

NOVEL AMIDE DERIVATIVES AND MEDICINAL USE THEREOF UGS

The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like]. Moreover, they are useful as a therapeutic or prophylactic agent for the infectious diseases caused by bacteria and virus that invade via a C5a receptor.

Indane or dihydroindole derivatives

The present invention relates to substituted indane or dihydroindole compounds of Formula (I) wherein A is an indole. These compounds have high affinity for D4receptors.