629624-25-5Relevant academic research and scientific papers
Intramolecular carbolithiation promoted by a DTBB-catalysed chlorine-lithium exchange
Yus, Miguel,Ortiz, Rosa,Huerta, Fernando F.
, p. 8525 - 8542 (2007/10/03)
The reaction of 6-chlorohex-1-ene 1 with lithium powder and a catalytic amount of 4,4′-di-tert-butylbiphenyl (DTBB, 5% molar) in THF at -78°C gives the corresponding organolithium intermediate 2, which by reaction with different electrophiles affords, aft
