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Usage

Uses

Used in Pharmaceutical Industry:
6-Chloro-N-(3-pyridinylmethyl)-2-pyrazinamine is used as an antibiotic for the treatment of tuberculosis. It is employed for its ability to inhibit the formation of cell walls in the bacteria responsible for the disease, thereby aiding in the management and eradication of tuberculosis infections.
Used in Public Health Initiatives:
6-Chloro-N-(3-pyridinylmethyl)-2-pyrazinamine is utilized as a critical component in global efforts to combat tuberculosis. Its inclusion in standard medication regimens contributes to the control and reduction of this widespread public health issue.

Upstream product

• 3731-52-0 3-Aminomethylpyridine 
• 4774-14-5 2,6-dichloropyrazine 

Relevant academic research and scientific papers

INHIBITORS OF SARM1

The present disclosure provides compounds and methods useful for inhibiting SARM1 and/or treating and/or preventing axonal degeneration.

SELECTIVE KINASE INHIBITORS

A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C1-4 alkyl, O, S, SO2, CO or CS and X1, X2, X3 and X4 are optionally substituted by 9 specific substituents or one can be nitrogen. Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I).

PROTEIN KINASE INHIBITORS

A compound of general formula (I) or pharmaceutically acceptable salts, hydrates, solvates, crystal forms of diastereomers thereof is described. A method of treating protein kinase-associated disease states using the compound of Formula (I) is also described.