62967-00-4

Upstream product

• 75554-04-0 ethyl 2,3-dichloro-4-(4-nitrobenzoyl)phenoxyacetate 
• 127-06-0 acetone oxime 
• 622-32-2 (Z)-benzaldehyde oxime 
• 62967-04-8 4-(4-nitrobenzoyl)-2,3-dichlorophenoxy acetic acid 
• 62966-99-8 4-(4-methoxybenzoyl)-2,3-dichlorophenoxy acetic acid 

Downstream Products

• 78235-49-1 2,3-dichloro-4-<3-<(2-chloroacetamido)methyl>-4-hydroxybenzoyl>phenoxyacetic acid 
• 87181-08-6 ethyl <2,3-dichloro-4-(4-hydroxybenzyl)phenoxy>acetate 
• 87181-09-7 ethyl <2,3-dichloro-4-<4-hydroxy-3-<(2-chloroacetyl)aminomethyl>benzyl>phenoxy>acetate 
• 87181-10-0 ethyl <2,3-dichloro-4-<3-(aminomethyl)-4-hydroxybenzyl>phenoxy>acetate hydrochloride 
• 78235-15-1 ethyl <2,3-dichloro-4-<4-hydroxy-3-<(2-chloroacetyl)aminomethyl>benzyl>phenoxy>acetic acid 
• 92270-69-4 [2,3-Dichloro-4-(4-hydroxy-3,5-bis-piperidin-1-ylmethyl-benzoyl)-phenoxy]-acetic acid ethyl ester 
• 92270-68-3 [2,3-Dichloro-4-(4-hydroxy-3,5-bis-pyrrolidin-1-ylmethyl-benzoyl)-phenoxy]-acetic acid ethyl ester 
• 92270-66-1 [4-(3,5-Bis-dimethylaminomethyl-4-hydroxy-benzoyl)-2,3-dichloro-phenoxy]-acetic acid ethyl ester 
• 92270-54-7 ethyl {2,3-dichloro-4-[3-(guanidinomethyl)-4-hydroxybenzoyl]phenoxy}acetate 
• 78235-71-9 ethyl <2,3-dichloro-4<3-(aminomethyl)-4-hydroxy-5-iodobenzoyl>phenoxy>acetate 
• 78235-69-5 ethyl <2,3-dichloro-4-<3-<(dimehylamino)methyl>-4-hydroxybenzoyl>phenoxy>acetate 
• 82241-61-0 ethyl <2,3-dichloro-4-<3,5-bis(aminomethyl)-4-hydroxybenzoyl>phenoxy>acetate 
• 78235-73-1 <2,3-dichloro-4-<3-(aminomethyl)-4-hydroxybenzoyl>phenoxy>acetic acid 
• 92270-56-9 ethyl {2,3-dichloro-4-[3-(aminomethyl)-4-methoxybenzoyl]phenoxy}acetate hydrobromide 

Relevant academic research and scientific papers

[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 1. Effects of nitrogen and aromatic nuclear substitution

A series of Mannich bases and aminomethyl derivatives of ethyl [2,3-dichloro-4-(4-hydroxybenzoyl)phenoxy]acetate were synthesized and tested for saluretic and diuretic activities. The effects of nitrogen and aromatic nuclear substitution, reorientation of

Process for making 4-aroyl-substituted phenoxyacetic acids

2,3-Dichloro-4-(hydroxybenzoyl)phenoxyacetic acid, its analogs and their salts are powerful uricosuric diuretics; they can be made in a one-pot reaction from a loweralkyl 2,3-dichloro-4-(nitrobenzoyl)phenoxyacetate or its analogs.

4-Aroyl-substituted phenoxy acetic acids

This invention provides 4-aroyl substituted phenoxy acetic acids and tetrazoles of the formula STR1 wherein R is a phenyl ring, a substituted phenyl ring, or naphthyl; R1 is --CH2 COOH or methyl tetrazole, and X1 and X2 are each a halogen or loweralkyl, or when taken together form with the two attached carbons a phenyl ring. These compounds are useful as antihypertensive agents, diuretics and uricosuric agents.