85297-76-3

Upstream product

• 78235-73-1 <2,3-dichloro-4-<3-(aminomethyl)-4-hydroxybenzoyl>phenoxy>acetic acid 
• 78235-49-1 2,3-dichloro-4-<3-<(2-chloroacetamido)methyl>-4-hydroxybenzoyl>phenoxyacetic acid 
• 75554-04-0 ethyl 2,3-dichloro-4-(4-nitrobenzoyl)phenoxyacetate 
• 62967-00-4 2,3-dichloro-4-(4'-hydroxybenzoyl)-phenoxyacetic acid 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 78235-46-8 ethyl {2,3-dichloro-4-[3-(aminomethyl)-4-hydroxybenzoyl]phenoxy}acetate hydrochloride 
• 78235-72-0 ethyl {2,3-dichloro-4-[3-(aminomethyl)-4-hydroxybenzoyl]phenoxy}acetate 

Downstream Products

• 85297-75-2 [5-(4-Carbamoylmethoxy-2,3-dichloro-benzoyl)-2-hydroxy-benzyl]-carbamic acid benzyl ester 
• 82241-45-0 <2,3-dichloro-4-<3-(aminomethyl)-4-hydroxybenzoyl>phenoxy>acetamide hydrobromide 
• 85297-78-5 <4-(2-aminoethoxy)-2,3-dichlorophenyl><3-(aminomethyl)-4-hydroxyphenyl>methanone dihydrochloride 
• 85297-77-4 <2,3-dichloro-4-<3-(benzyloxycarboxamido)methyl-4-hydroxybenzoyl>phenoxy>acetonitrile 

Relevant academic research and scientific papers

[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 1. Effects of nitrogen and aromatic nuclear substitution

A series of Mannich bases and aminomethyl derivatives of ethyl [2,3-dichloro-4-(4-hydroxybenzoyl)phenoxy]acetate were synthesized and tested for saluretic and diuretic activities. The effects of nitrogen and aromatic nuclear substitution, reorientation of

acetic Acid Esters. A New Class of High-Ceiling Diuretics. 2. Modifications of the Oxyacetic Side Chain

The discovery of high-ceiling natriuretic activity from a series of aminomethyl derivatives of ethyl acetate prompted our continued investigation of this new class of (aryloxy)acetic acid diuretics.Systematic alte