6297-12-7

Usage

Classification

Nonsteroidal anti-inflammatory drug (NSAID)

Purpose

Relieves pain, reduces inflammation, and lowers fever

Mechanism of Action

Inhibits the production of prostaglandins, which cause pain and inflammation

Common Uses

Treating arthritis, menstrual cramps, and mild to moderate pain

Available Forms

Oral tablets, capsules, and topical creams or gels

Prescription

Typically prescribed by a doctor based on the patient's specific needs

Side Effects

Stomach upset, heartburn, dizziness

Risks

Increased risk of heart attack or stroke if used in high doses or for prolonged periods

Usage

Should be used only as directed by a healthcare professional

Upstream product

• 2905-65-9 methyl 3-chlorobenzoate 
• 99-02-5 3'-Chloroacetophenone 
• 618-46-2 m-Chlorobenzoyl chloride 
• 123-54-6 acetylacetone 

Downstream Products

• 50625-49-5 m-Chlorobenzoyl azide 
• 1393093-36-1 C₂₁H₁₄Cl₂N₂ 
• 1393092-92-6 2,4-bis(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine 
• 1393092-90-4 2,4-bis(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine 
• 33098-31-6 4,6-bis-(3-chloro-phenyl)-1-methyl-1H-pyrimidin-2-one 

Relevant academic research and scientific papers

Ag-Catalyzed Insertion of Alkynyl Carbenes into C-C Bonds of β-Ketocarbonyls: A Formal C(sp2) Insertion

Here we report a silver-catalyzed alkynyl carbene insertion into β-ketocarbonyls using alkynyl N-nosylhydrazones as alkynyl carbene precursors, which provides access to trisubstituted allenyl ketones. This reaction represents the first example of an alkynyl carbene insertion into a C-C σ bond, affording products homologated with an sp2 carbon center. The products are useful substrates for further transformations. Experimental investigations and theoretical calculations suggest the reaction proceeds through a stepwise enol cyclopropanation/retro-aldol pathway.

Triboluminescence of centrosymmetric lanthanide β-diketonate complexes with aggregation-induced emission

Triboluminescence (TL) is a form of light emission induced upon mechanical forces on the material. However, our understanding of this phenomenon is still unclear and more examples are therefore needed in order to elucidate its mechanism. In this work, two

A facile route to convert acetylacetone into other β-diketones with acyl chlorides promoted by samarium triiodide

Reaction of acetylacetone with acyl chlorides in the presence of SmI3 gave β-diketones RCOCH2COCH3 (I) or RCOCH2COR (II) in good yields under mild and neutral conditions.