62972-22-9Relevant academic research and scientific papers
Efficient synthesis of 2-alkylidene-4h-3,1-benzoxathiin-4-ones and determination of their double bond configuration
Shimizu, Masao,Yamanaka, Masaki,Ando, Wataru,Shimada, Shigeru,Konakahara, Takeo,Sakai, Norio
, p. 981 - 993 (2014/04/17)
2-Alkylidene-4H-3,1-benzoxathiin-4-ones were efficiently synthesized by reaction of 2-(acylthio)benzoic acids with condensation reagents in the presence of base. The E and Z isomers of the products were distinguished by comparison of the chemical shifts o
Synthesis and characterization of an anticoagulant 4-hydroxy-1-thiocoumarin by FTIR, FT-Raman, NMR, DFT, NBO and HOMO-LUMO analysis
Arjunan,Santhanam,Sakiladevi,Marchewka,Mohan
, p. 305 - 316 (2013/05/09)
Experimental and theoretical investigations on the molecular structural, electronic and the vibrational characteristics of 4-hydroxy-1-thiocoumarin are presented. Conformational analysis was carried out to obtain the more stable configuration of the compo
New nuclear transcription factors regulators
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Page/Page column 5-6, (2008/06/13)
The present invention relates to novel compounds that are nuclear transcription factors (NTF) regulators. The present invention also provides methods for treating, preventing and/or reducing inflammation-associated diseases by regulating NTF in the cardiovascular, connective tissue, pulmonary, gastrointestinal, respiratory, urogenital, nervous, or cutaneous systems as well as tumoral and infective diseases employing said compounds. The present invention is based on the discovery that it is possible to link regulators of NTF to a pharmacologically active compound helpful for treating disorders in the cardiovascular, connective tissue, pulmonary, gastrointestinal, respiratory, urogenital, nervous, or cutaneous systems or tumoral and infective diseases. The resulting compounds have good bioavailability, increased activity and/or safety.
Efficient and practical syntheses of benzothiopyran derivatives
Jung, Jae-Chul,Kim, Ju-Cheun,Park, Oee-Sook
, p. 1193 - 1203 (2007/10/03)
Concise and inexpensive methods for the preparation of 4-hydroxy-1- thiocoumarin and 2-methylthiochromone from 2-mercaptobenzoic acid are described, which should be readily amenable to large scale synthesis.
Aspects of Tautomerism: Part X - Neighbouring Group Effects on the Structure and Reactivity Patterns of Acid Chlorides
Bhatt, M. Vivekananda,El Ashry, Shaker H.,Somayaji, Vishwanatha
, p. 473 - 486 (2007/10/02)
The influence of neighbouring groups on the structure and reactivity patterns of over one hundred acid chlorides derived from γ- and δ-keto acids, 1,2- and 1,3-dicarboxylic acid half-esters and diacid chlorides have been examined.Contrary to reports in the literature, text books and monographs, evidence has been obtained for the non-existence of tautomerism between the isomeric pairs of either acid chlorides or half-ester acid chlorides.ce.
