629921-36-4

Upstream product

• 629955-38-0 (2R,4S)-2-(4-fluoro-2-methyl-phenyl)-4-(2-hydroxyethylaminocarbonyloxy)piperidine 
• 629956-38-3 N-(3,5-bistrifluoromethylbenzyl)-N-methyl-aminocarbonyl chloride 
• 629922-66-3 (2R,4S)-1-{N-(3,5-bistrifluoromethylbenzyl)-N-methyl}amino-carbonyl-2-(4-fluoro-2-methylphenyl)-4-hydroxypiperidine 
• 141-43-5 ethanolamine 
• 1885-14-9 phenyl chloroformate 

Relevant academic research and scientific papers

CRYSTALLINE FORM OF PIPERIDINE COMPOUND

The present invention is to provide a crystalline form of (2R,4S)-1-{N-(3,5-bistrifluoromethylbenzyl)-N-methyl}aminocarbonyl-2-(4-fluoro-2-methylphenyl)-4-(2-hydroxyethylaminocarbonyloxy)piperidine or a solvate thereof.

PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PIPERIDINE COMPOUND

The present invention relates to a method for preparing a syn-form piperidine compound represented by general formula [I]: wherein, bold lines represent bonds in which substituents at positions 2 and 4 of a piperidine ring are in the syn configuration, an

NOVEL PIPERIDINE COMPOUND

The present invention provides a novel piperidine compound of the formula [I]: wherein Ring A represents an optionally substituted benzene ring, Ring B represents an optionally substituted benzene ring, R1 represents an optionally substituted alkyl group, an optionally substituted hydroxyl group, etc., or a group of the formula: (a) wherein R11 and R12 are the same or different, and each represents hydrogen atom, a substituted carbonyl group, a substituted sulfonyl group, an optionally substituted alkyl group, etc., R2 represents hydrogen atom, etc., Z represents oxygen atom or a group represented by -N(R3)-, R3 represents hydrogen atom or an alkyl group, etc., R4 represents hydrogen atom or an alkyl group, etc.,or a pharmaceutically acceptable salt thereof.