63002-50-6

Upstream product

• 199933-82-9 1-(4-hydroxybenzoyl)-2-(chloroacetyl)hydrazine 
• 5351-23-5 4-hydroxybenzoic acid hydrazide 
• 79-04-9 chloroacetyl chloride 
• 199938-12-0 N-(3,3-diphenylpropyl)homopiperazine 

Relevant academic research and scientific papers

DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS

Cyclic diamines of formula (I) or their pharmacologically acceptable acid addition salts, and their medical applications are described. These compounds inhibit the action of chemokines such as MIP-la and/or MCP-l on target cells, and are useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.