630107-97-0Relevant academic research and scientific papers
PYRIMIDINE COMPOUNDS HAVING PHOSPHONATE GROUPS AS ANTIVIRAL NUCLEOTIDE ANALOGS
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Page 29-30, (2010/02/10)
Novel compounds are provided having formula (I) where R1, R2, R3, R4, Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I).
5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy) ethoxy]pyrimidines-Acyclic Nucleoside Phosphonate Analogues with Antiviral Activity
Hocková, Dana,Holy, Antonín,Masojídková, Milena,Andrei, Graciela,Snoeck, Robert,De Clercq, Erik,Balzarini, Jan
, p. 5064 - 5073 (2007/10/03)
2,4-Diamino-6-hydroxypyrimidines substituted in position 5 by an allyl, benzyl, cyanomethyl, ethoxycarbonylmethyl, phenyl, cyclopropyl, or methyl group were prepared either by C5-alkylation or by formation of the pyrimidine ring by cyclization. Their alky
