63011-97-2

Basic information

• Product Name: (ACETYLOXY)(2-THIENYL)METHYL ACETATE
• Synonyms: (ACETYLOXY)(2-THIENYL)METHYL ACETATE;THIOPHENE-2-METHANEDIOL DIACETATE
• CAS NO: 63011-97-2
• Molecular Formula: C₉H₁₀O₄S
• Molecular Weight: 214.24
• Mol File: 63011-97-2.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 154 °C
• Flash Point: 132°C
• Appearance: /
• Density: 1.267g/cm³
• Vapor Pressure: 0.00161mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: (ACETYLOXY)(2-THIENYL)METHYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: (ACETYLOXY)(2-THIENYL)METHYL ACETATE(63011-97-2)
• EPA Substance Registry System: (ACETYLOXY)(2-THIENYL)METHYL ACETATE(63011-97-2)

Safety Data

• Hazardous Substances Data: 63011-97-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 1356, 1952 DOI: 10.1021/ja01125a519

InChI:InChI=1/C9H10O4S/c1-6(10)12-9(13-7(2)11)8-4-3-5-14-8/h3-5,9H,1-2H3

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 108-24-7 acetic anhydride 

Downstream Products

• 636-72-6 2-thiophenemethanol 
• 5832-01-9 methyl 5-nitrothiophene-2-carboxylate 
• 6286-12-0 5-nitro-2-thiophene semicarbazone 
• 84653-70-3 2-(5-nitrothiophen-2-ylmethylene)malononitrile 
• 6317-37-9 5-nitrothiophene-2-carboxylic acid 
• 4521-33-9 5-nitro-2-thiophenecarboxaldehyde 
• 70380-70-0 5-(thiophen-2-yl)oxazole 
• 98-03-3 thiophene-2-carbaldehyde 
• 14289-24-8 5-nitrothiophene-2-carboxaldehyde diacetate 
• 63011-99-4 2-diacetoxymethyl-4-nitro-thiophene 

Relevant articles and documents

Application of poly(Vinylbenzyltrimethylammonium tribromide) resin as an efficient polymeric catalyst in the acetalization and diacetylation of benzaldehydes

The applications of a new supported tribromide reagent (poly(vinylbenzyltrimethylammonium tribromide) resin) were reported. This supported tribromide resin was used as a catalyst in the acetalization and diacetylation of benzaldehydes under mild conditions with high efficiency. The effects of solvents, and amount of the supported tribromide resin on the reactions were investigated. Under the optimal conditions, most of acetal and 1,1-diacetates of benzaldehydes were selectively obtained in excellent yields.

The studies on chemoselective promiscuous activity of hydrolases on acylals transformations

Chemoselective, mild and convenient protocol for the hydrolysis of the synthetically relevant acylals via promiscuous enzyme-catalyzed hydrolysis has been developed. It has been shown that promiscuous activity of the used hydrolases dominates their native activity related with carboxylic esters hydrolysis. The main advantage of the present methodology is that it can be conducted under neutral conditions at room temperature. Moreover, complete deprotection of acylals takes place within 10–20 min. Developed protocol can be used with compounds having a variety of hydrolytic labile groups since the cleavage is proceeded under neutral conditions and occurs exclusively on acylal moiety. Further this protocol was extended by the tandem Passerini multicomponent reaction leading to the α-acetoxy amides using acylals as the surrogates of the carbonyl components to P-MCR.

Formation of benzylidenes-diacetates catalyzed by activated zeolite "LZY-562" and clay (K10/ZnCl2): An unexpected functional selectivity

Activated zeolites LZY-562 and clay montmorillonite K10 at room temperature without solvent catalyzes the synthesis of benzylidenesdiacetates from carbonyl compounds. A chemoselectivity was observed between aldehydes and ketones, between the different aldehydes and ketones as well.