630110-70-2Relevant articles and documents
Synthesis of homocarbonyltopsentine derivatives
Montagne, Cyril,Fournet, Guy,Joseph, Benoit
, p. 136 - 146 (2007/10/03)
Homocarbonyltopsentines I are known to exhibit interesting anti-inflammatory activity in vivo. In order to study the role of the heterocycles in the modulation of their activity, several analogues in which indoles were replaced either by substituted indol
An efficient synthetic route to homocarbonyltopsentine
Montagne, Cyril,Fournet, Guy,Joseph, Beno?t
, p. 1533 - 1535 (2007/10/03)
Efficient synthesis of homocarbonyltopsentine Ia, starting from readily available triiodoimidazole 9 and 3-formylindoles 2 and 18 is described. The key steps of the synthesis are selective halogen-metal exchanges at the imidazole nucleus and subsequent ad