57476-50-3

Basic information

• Product Name: TERT-BUTYL 3-FORMYL-1H-INDOLE-1-CARBOXYLATE
• Synonyms: TERT-BUTYL 3-FORMYL-1H-INDOLE-1-CARBOXYLATE;TERT-BUTYL 3-FORMYLINDOLE-1-CARBOXYLATE;INDOLE-3-CARBOXALDEHYDE, N-BOC PROTECTED;3-FORMYLINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;3-FORMYLINDOLE, N-BOC PROTECTED;1-Boc-3-formylindole;3-Formylindole-1-carboxylic acid t-butyl ester;1H-Indole-3-carboxaldehyde, N-BOC protected
• CAS NO: 57476-50-3
• Molecular Formula: C₁₄H₁₅NO₃
• Molecular Weight: 245.27
• Mol File: 57476-50-3.mol
• Article Data: 72

Chemical Properties

• Melting Point: 119-121°C
• Boiling Point: 380 °C at 760 mmHg
• Flash Point: 183.6 °C
• Appearance: /
• Density: 1.13 g/cm³
• Vapor Pressure: 5.63E-06mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: TERT-BUTYL 3-FORMYL-1H-INDOLE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 3-FORMYL-1H-INDOLE-1-CARBOXYLATE(57476-50-3)
• EPA Substance Registry System: TERT-BUTYL 3-FORMYL-1H-INDOLE-1-CARBOXYLATE(57476-50-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 57476-50-3(Hazardous Substances Data)

Usage

General Description

Tert-Butyl 3-formyl-1h-indole-1-carboxylate is a chemical compound with a molecular formula C17H17NO3. It is a derivative of indole, a heterocyclic aromatic organic compound. tert-Butyl 3-formyl-1h-indole-1-carboxylate is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active molecules. Tert-Butyl 3-formyl-1h-indole-1-carboxylate is known for its potential pharmaceutical properties and is being studied for its potential therapeutic applications.

InChI:InChI=1/C14H15NO3/c1-14(2,3)18-13(17)15-8-10(9-16)11-6-4-5-7-12(11)15/h4-9H,1-3H3

Upstream product

• 1407968-48-2 3-[N-(tert-butoxycarbonyl)-N-(2-iodophenyl)amino]propanal 
• 1196-69-6 1H-indole-5-carboxaldehyde 
• 24424-99-5 di-tert-butyl dicarbonate 
• 675606-20-9 1-(tert-butoxycarbonyl)-1H-indole-3-carboxylic acid 
• 75400-67-8 indole-1-carboxylic acid tert-butyl ester 
• 75-50-3 trimethylamine 
• 637-69-4 4-Methoxystyrene 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 
• 862704-32-3 tert-butyl 3-(chloromethyl)-1H-indole-1-carboxylate 
• 5470-70-2 Methyl 6-methylnicotinate 
• 120-72-9 indole 
• 487-89-8 Indole-3-carboxaldehyde 
• 34619-03-9 tert-butyldicarbonate 
• 96551-22-3 t-butyl 3-hydroxymethylindole-1-carboxylate 

Downstream Products

• 130680-70-5 N-benzyloxycarbonyl-N'-(tert-butyloxycarbonyl)-Z-α,β-didehydrotryptophan 
• 130680-70-5 methyl (E)-3-(1-tert-butoxycarbonylindol-3-yl)-2-(carbobenzoxyamino)acrylate 
• 89525-14-4 3-((E)-2-Benzyloxycarbonylamino-2-ethoxycarbonyl-vinyl)-indole-1-carboxylic acid tert-butyl ester 
• 89525-15-5 ethyl (Z)-N^α-benzyloxycarbonyl-Nⁱⁿ-tert-butyloxycarbonyl-α,β-didehydrotriptophanate 
• 96551-22-3 t-butyl 3-hydroxymethylindole-1-carboxylate 
• 80-73-9 1,3-dimethyl-2-imidazolidinone 
• 487-89-8 Indole-3-carboxaldehyde 
• 494803-87-1 3-{2-[2-(tert-butoxycarbonyl-methyl-amino)-3-phenyl-propionylamino]-1-hydroxy-ethyl}-indole-1-carboxylic acid tert-butyl ester 
• 105748-59-2 brassinin 
• 105748-58-1 cyclobrassinin 
• 188988-46-7 tert-butyl 3-(aminomethyl)-1H-indole-1-carboxylate 
• 1292799-36-0 1-{[(1-tert-butoxycarbonylindol-3-yl)methyl]methylamino}-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol 

Relevant articles and documents

NOVEL COMPOUND AND COMPOSITION FOR PREVENTION OR TREATMENT OF RESPIRATORY DISEASES COMPRISING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel compound, and a composition for preventing or treating of respiratory disease comprising the novel compound, E- or Z-isomer thereof, optical isomer thereof, a mixture of two isomers thereof, precursor thereof, pharmaceutically acceptable salt thereof or solvate thereof as an active ingredient.

4CzIPN catalyzed photochemical oxidation of benzylic alcohols

A green photoredox oxidation of benzylic primary and secondary alcohols to aldehydes and ketones with air as an oxidant was reported. The oxidation shows broad substrate scope and excellent selectivity over benzylic alcohols to the aliphatic alcohols. Further mechanistic studies revealed a quinuclidine mediated HAT process, and blue LEDs promoted 4CzlPN (1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene) photoredox cycle were involved in our oxidation.