630121-86-7

Usage

Uses

Used in Organic Synthesis:
Tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate is used as a reagent in organic synthesis for its ability to contribute to the formation of a variety of complex organic molecules. Its unique structure allows it to participate in numerous chemical reactions, facilitating the synthesis of target compounds with specific properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate is utilized as a building block for the preparation of pharmaceuticals. Its incorporation into drug molecules can potentially enhance their therapeutic effects, selectivity, and pharmacokinetic profiles, making it an essential component in the development of new medications.
Used in Agrochemical Development:
Tert-Butyl 3-(((trifluoroMethyl)sulfonyl)oxy)-2,5-dihydro-1H-pyrrole-1-carboxylate also finds application in the agrochemical sector, where it serves as a precursor for the synthesis of agrochemicals. Its use in this industry aids in the development of more effective and targeted pesticides, herbicides, and other agricultural chemicals.
Used as an Intermediate in Synthesis:
This chemical is also employed as an intermediate in the synthesis of other organic compounds. Its role in these processes is crucial for the production of a wide range of chemical entities, further emphasizing its multifaceted utility in the realm of chemical research and development.

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 101385-93-7 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 103057-44-9 N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 145100-51-2 N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide 

Downstream Products

• 212127-83-8 tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihydropyrrole-1-carboxylate 
• 1094217-59-0 1-tert-butoxycarbonyl-3-(3-hydroxyphenyl)pyrrolidine 
• 912971-58-5 tert-butyl 3-(2-(2-methoxyphenyl)-1H-indol-5-yl)-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1393901-75-1 tert-butyl 3-(4-nitrophenyl)-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1204331-72-5 3-(4-carboxy-2-trifluoromethyl-phenyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1204331-71-4 3-(4-carboxy-2-trifluoromethyl-phenyl)-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 
• 1204331-70-3 3-(4-cyano-2-trifluoromethyl-phenyl)-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

PURINES AND METHODS OF THEIR USE

Disclosed are compounds useful in the treatment of neurological disorders. The compounds described herein, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological diseases.

BICYCLIC HETEROARENES AND METHODS OF THEIR USE

Disclosed are compounds useful in the treatment of neurological disorders. The compounds described herein, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological diseases.

Substituted aza five-membered ring derivative and application thereof in medicine

The invention discloses a substituted aza-five-membered ring derivative and application thereof to medicines. , The invention provides a substituted aza five-membered ring compound or a stereoisomer, a tautomer, an oxynitride, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and a pharmaceutical composition containing the compound of the present invention. The invention also discloses application of the compound or the pharmaceutical composition of the compound in preparation of a medicament for treating PDE4 related diseases such as atopic dermatitis (AD) or chronic obstructive pulmonary disease (COPD).

NAMPT MODULATORS

Provided are compounds of Formula (II) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, and p are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (II), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (II), or a pharmaceutically acceptable salt thereof.

INDOLO HEPTAMYL OXIME ANALOGUE AS PARP INHIBITOR

Disclosed is a type of indolo heptamyl oxime compounds as a PARP inhibitor. Specifically disclosed are a compound as represented by formula (II) and a pharmaceutically acceptable salt thereof.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME

Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.

NOVEL COMPOUNDS

The invention relates to compounds of Formula (I) and their use in therapy, for example in the treatment of mycobacterial infections or in the treatment of diseases caused by mycobacterium, such as tuberculosis.

Tetrahydropyrrole compound, preparation method, pharmaceutical composition and application thereof

The invention discloses a tetrahydropyrrole compound and a preparation method, a pharmaceutical composition and application thereof. The tetrahydropyrrole compound of the invention is as shown in thegeneral formula (I). The tetrahydropyrrole compound of the invention has an excellent inhibitory effect on the positive symptom of schizophrenia, and has equivalent or stronger efficacy in comparisonwith the positive medicine olanzapine. In addition, the compound of the invention has a dual inhibitory effect on a D2 receptor and a DAT receptor, can effectively treat schizophrenia and improve negative symptoms and cognitive functions, and helps reduce side-effect of centrum and secretion of lactogen.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.