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2-Pyrimidinamine, N-methyl-4-(4-nitrophenoxy)-, also known as 4-(4-Nitrophenoxy)-N-methylpyrimidin-2-amine, is a chemical compound with the molecular formula C11H11N3O3. It is a derivative of pyrimidinamine, featuring a methyl group attached to the nitrogen atom at position 2 and a 4-nitrophenoxy group at position 4. 2-Pyrimidinamine, N-methyl-4-(4-nitrophenoxy)- is characterized by its yellow crystalline appearance and is soluble in various organic solvents. It has potential applications in the synthesis of pharmaceuticals and agrochemicals, particularly as an intermediate in the production of certain pesticides and drugs. Due to its reactivity and functional groups, it is important to handle 2-Pyrimidinamine, N-methyl-4-(4-nitrophenoxy)- with care, adhering to proper safety protocols.

630126-01-1

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630126-01-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 630126-01-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,0,1,2 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 630126-01:
(8*6)+(7*3)+(6*0)+(5*1)+(4*2)+(3*6)+(2*0)+(1*1)=101
101 % 10 = 1
So 630126-01-1 is a valid CAS Registry Number.

630126-01-1Upstream product

630126-01-1Relevant academic research and scientific papers

DIARYL UREA DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

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Page/Page column 97, (2008/06/13)

The invention relates to the use of diaryl urea derivatives for the manufacture of pharmaceutical compositions for the treatment of RET dependent disorders, especially RET dependent tumor diseases. The invention further relates to novel N-[4-(pyrimidin-4-yloxy)-phenyl]-N’-phenyl-urea derivatives and their use in the treatment of the animal or human body, especially in the treatment of a protein kinase dependent disease, to pharmaceutical compositions comprising such novel N-[4-pyrimidin-4-yloxy)-phenyl]-N’-phenyl-urea derivatives and to the use of such novel N-[4-(pyrimidin-4-yloxy)-phenyl]-N’-phenyl-urea derivatives for the preparation of pharmaceutical compositions for use in the treatment of protein kinase dependent diseases, especially of proliferative diseases, such as tumour diseases.

DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

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Page 138, (2008/06/13)

The invention relates to the use of diaryl urea derivatives in the treatment of protein kinase dependent diseases or for the manufacture of pharmaceutical compositions for use in the treatment of said diseases, methods of use of diaryl urea derivatives in the treatment of said diseases, pharmaceutical preparations comprising diaryl urea derivatives for the treatment of said diseases, diaryl urea derivatives for use in the treatment of said diseases, novel diaryl urea derivatives, pharmaceutical preparations comprising these novel diaryl urea derivatives, processes for the manufacture of the novel diaryl urea derivatives, the use or methods of use of the novel diaryl urea derivatives as mentioned above, and/or these novel diaryl urea derivatives for use in the treatment of the animal or human body.

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