630128-01-7

Basic information

• Product Name: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate
• Synonyms: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate;Hexanedioic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, 6-methyl 1-(phenylmethyl) ester, (2S)-;2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-hexanedioic acid 6-methyl 1-(phenylmethyl) ester;(S)-1-benzyl 6-methyl 2-((tert-butoxycarbonyl)amino)-4-oxohexanedioate
• CAS NO: 630128-01-7
• Molecular Formula: C₁₉H₂₅NO₇
• Molecular Weight: 379.4043
• EINECS: -0
• Mol File: 630128-01-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 69-72 °C
• Boiling Point: 517.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.183±0.06 g/cm3(Predicted)
• PKA: 10.21±0.46(Predicted)
• CAS DataBase Reference: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate(630128-01-7)
• EPA Substance Registry System: Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate(630128-01-7)

Safety Data

• Hazardous Substances Data: 630128-01-7(Hazardous Substances Data)

Usage

General Description

Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate is a chemical compound that is commonly used in organic synthesis. It belongs to the family of carboxylic acid derivatives and contains a benzyl group, a BOC-protected amine group, and a carbomethoxy group. Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate is often used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. It is also used in the production of various types of polymers and materials. Benzyl-2-N-BOC-5-carbomethoxy-4-oxo-pentanate is a versatile compound that is important in the field of organic chemistry and has a wide range of applications in industry.

Upstream product

• 844644-72-0 2-tert-butoxycarbonylamino-4-(2,2-dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidene)-4-hydroxy-butyric acid benzyl ester 
• 30925-18-9 2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester 
• 67-56-1 methanol 

Downstream Products

• 766514-49-2 1-O-2-S-[1'-benzyloxycarbonyl-2'-(4'-t-butoxycarbonylamino)-methylpropionate-1'-2'-ethenyl]-3,4,6-tri-O-benzyl-α-D-glucopyranoside 
• 1186468-33-6 C₄₃H₇₃NO₁₁SSi₂ 
• 630128-07-3 (4aS,6R,7R,8S,8aR)-7,8-Bis-benzyloxy-3-((S)-2-benzyloxycarbonyl-2-tert-butoxycarbonylamino-ethyl)-6-benzyloxymethyl-4-(2-trimethylsilanyl-ethanesulfonyl)-4,4a,6,7,8,8a-hexahydro-5-oxa-1-thia-4-aza-naphthalene-2-carboxylic acid methyl ester 
• 630128-10-8 (2R,3R,4S,4aR,7S,9aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-5-oxo-9-(2-trimethylsilanyl-ethanesulfonyl)-2,3,4,4a,5,6,7,8,9,9a-decahydro-1-oxa-10-thia-6,9-diaza-anthracene-7-carboxylic acid benzyl ester 
• 630128-03-9 (S)-2-tert-Butoxycarbonylamino-4-[(Z)-hydroxyimino]-hexanedioic acid 1-benzyl ester 6-methyl ester 

Relevant articles and documents

POLYMORPHIC FORM OF COMPOUND, PREPARATION METHOD AND USE THEREOF

The present disclosure relates to polymorphic forms of the compound methyl (3R,6S)-6-amino-sulfonylamino-1-(thiazol-2-yl)-3-(2,3,4-trifluorophenyl)-3,5,6,7-tetrahydropyrrolo[1,2-c]pyrimidin-4-formate (compound 1). The present disclosure further relates to

Synthesis of a Fluorescent-Labeled Bisbenzamidine Containing the Central (6,7-Dimethoxy-4-coumaryl)Alanine Building Block

The synthesis of an amino acid amide is reported, which contains two benzamidine cores, one placed in the amide part the other one within the sulfonyl N-capping group. The amino acid side chain bears the 6,7-dimethoxycoumarin fluorophore. The fluorescent amino acid was prepared by using the von-Pechmann reaction. The two corresponding nitrile groups of a precursor molecule were simultaneously converted to the amidine moieties by the Pinner reaction. The fluorescent properties of the final compound were determined.

A novel neoglycopeptide building block

The synthesis of a neoglycopeptide building block is described. The key step is a cycloaddition where the chemistry is orthogonal to standard glycosyl transfer methodology. Also described is some exploratory chemistry of the building block.