63013-55-8

Usage

InChI:InChI=1/C16H19BrO/c17-14-6-13(1-2-15(14)18)16-7-10-3-11(8-16)5-12(4-10)9-16/h1-2,6,10-12,18H,3-5,7-9H2

Upstream product

• 29799-07-3 4-adamantylphenol 
• 768-95-6 1-adamanthanol 
• 95-56-7 2-hydroxybromobenzene 

Downstream Products

• 35687-09-3 5-((3R,5R,7R)-adamantan-1-yl)-[1,1'-biphenyl]-2-ol 
• 1363648-63-8 4-(1-adamantyl)-2-bromo-6-[(dimethylamino)methyl]phenol 

Relevant academic research and scientific papers

Preparation method of tertiary amine compound

The invention provides a preparation method of a tertiary amine compound, and belongs to the technical field of organic chemistry. The preparation method of the tertiary amine compound comprises the following steps: performing a carbon-nitrogen coupling reaction on a compound of chemical formula 2 and a compound of chemical formula 3 to obtain a compound of chemical formula 4; and carrying out thecarbon-nitrogen coupling reaction on the compound of chemical formula 4 and a compound of chemical formula 5 to obtain the compound of chemical formula 1, wherein the chemical formula 1, the chemicalformula 2, the chemical formula 3, the chemical formula 4 and the chemical formula 5 are shown in the description.

Preparation method of triphenylamine derivative containing adamantyl group

The invention provides a preparation method of a triphenylamine derivative containing adamantyl group. At first, aryl halogenated adamantane or aryl adamantane ester is used to react with a primary aromatic amine. After the reaction, no separation and purification are carried out, and halogenated aromatic hydrocarbons are directly put into the reaction to carry out the reaction. In this way, not only the reaction steps are few, but also the impurity content can be reduced, the yield of the product can be further improved, and the target product can be prepared in a higher yield. At that same time, the step of the invention is simple, the raw materials used are basic chemical raw materials, the yield is high, and the final prepared product has high purity, and the raw material cost, the practical operability and the work hours required for operation are greatly superior to the prior art, and the invention is very suitable for industrial production.

ANTIBIOTIC COMPOUNDS

The present application provides compounds and methods of treating bacterial infection, including bacterial infection caused by P. acnes.