29799-07-3

Basic information

• Product Name: 4-(1-ADAMANTYL)PHENOL
• Synonyms: AKOS BC-0514;4-(1-ADAMANTYL)PHENOL;1-(4-HYDROXYPHENYL)ADAMANTANE;LABOTEST-BB LT00007821;IFLAB-BB F0701-0062;SALOR-INT L496022-1EA;P-(1-ADAMANTYL)PHENOL;Adamantylphenol
• CAS NO: 29799-07-3
• Molecular Formula: C₁₆H₂₀O
• Molecular Weight: 228.33
• Product Categories: Adamantane derivatives;Adamantanes;Organic Building Blocks;Oxygen Compounds;Phenols;Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 29799-07-3.mol
• Article Data: 18

Chemical Properties

• Melting Point: 181-183 °C(lit.)
• Boiling Point: 361.6 °C at 760 mmHg
• Flash Point: 190.3 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 9.87E-06mmHg at 25°C
• Refractive Index: 1.612
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)
• PKA: 10.02±0.15(Predicted)
• CAS DataBase Reference: 4-(1-ADAMANTYL)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-ADAMANTYL)PHENOL(29799-07-3)
• EPA Substance Registry System: 4-(1-ADAMANTYL)PHENOL(29799-07-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 29799-07-3(Hazardous Substances Data)

Usage

Chemical Properties

White Crystals

Uses

4-(1-Adamantyl)phenol is used to study inhibitors of oral bacteria.

InChI:InChI=1/C16H20O/c17-15-3-1-14(2-4-15)16-8-11-5-12(9-16)7-13(6-11)10-16/h1-4,11-13,17H,5-10H2

Upstream product

• 768-90-1 1-Adamantyl bromide 
• 15288-53-6 o-(trimethylsilyl)phenol 
• 768-95-6 1-adamanthanol 
• 108-95-2 phenol 
• 100-66-3 methoxybenzene 
• 24569-89-9 1,3-dehydroadamantane 
• 935-56-8 1-chloroadamantane 
• 726-94-3 1-(4-methoxyphenyl)adamantane 

Downstream Products

• 351330-03-5 4-(1-adamantyl)phenyl glycidyl ether 
• 1156455-38-7 (2R,4R)-4-[{(4-adamantan-1-yl)phenoxy}methyl]-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolane 
• 258355-02-1 4-(1-adamantyl)phenyl methacrylate 
• 1414335-39-9 methyl 3-[4-(4-adamantan-1-ylphenoxy)butanamido]benzoate 
• 1414335-38-8 methyl 3-(3-(4-(adamantan-1-yl)phenoxy)propanamido)benzoate 
• 926201-37-8 3-(4-adamantan-1-yl-phenoxy)-propanoic acid 
• 160558-66-7 1-[4-(1-tricyclo[3.3.1.13,7]decyl)phenoxylethyl]piperidine 
• 223133-70-8 4-(4-adamantan-1-ylphenoxy)-2-(N-t-butoxycarbonyl-N-methylamino)aniline 

Relevant articles and documents

Thermal Stability Study of 4-(1-Adamantyl)phenol

Abstract: The thermal stability of 4-(1-adamantyl)phenol has been studied in the temperature range of 703–753 K, the components of the thermolysis reaction mixture have been identified, and the rate constants and parameters of the Arrhenius equation for t

LIGHT EMITTING DIODE AND DISPLAY DEVICE INCLUDING THE SAME

A light emitting diode of an embodiment includes a first electrode, a hole transport region disposed on the first electrode, an emission layer disposed on the hole transport region, an electron transport region disposed on the emission layer, and a second

Three-Component, Interrupted Radical Heck/Allylic Substitution Cascade Involving Unactivated Alkyl Bromides

Developing efficient and selective strategies to approach complex architectures containing (multi)stereogenic centers has been a long-standing synthetic challenge in both academia and industry. Catalytic cascade reactions represent a powerful means of rapidly leveraging molecular complexity from simple feedstocks. Unfortunately, carrying out cascade Heck-type reactions involving unactivated (tertiary) alkyl halides remains an unmet challenge owing to unavoidable β-hydride elimination. Herein, we show that a modular, practical, and general palladium-catalyzed, radical three-component coupling can indeed overcome the aforementioned limitations through an interrupted Heck/allylic substitution sequence mediated by visible light. Selective 1,4-difunctionalization of unactivated 1,3-dienes, such as butadiene, has been achieved by employing different commercially available nitrogen-, oxygen-, sulfur-, or carbon-based nucleophiles and unactivated alkyl bromides (>130 examples, mostly >95:5 E/Z, >20:1 rr). Sequential C(sp3)-C(sp3) and C-X (N, O, S) bonds have been constructed efficiently with a broad scope and high functional group tolerance. The flexibility and versatility of the strategy have been illustrated in a gram-scale reaction and streamlined syntheses of complex ether, sulfone, and tertiary amine products, some of which would be difficult to access via currently established methods.