63019-97-6

Usage

Uses

Used in Pharmaceutical Industry:
2'-METHYL-BIPHENYL-4-YLAMINE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs and enhance their efficacy.
Used in Dye Industry:
2'-METHYL-BIPHENYL-4-YLAMINE is used as a chemical intermediate in the production of dyes, contributing to the creation of a wide range of colorants for various applications.
Used in Organic Compounds Synthesis:
2'-METHYL-BIPHENYL-4-YLAMINE is used as a building block in the synthesis of other organic compounds, playing a crucial role in the development of new chemical entities for various industrial applications.

InChI:InChI=1/C13H13N/c1-10-9-12(14)7-8-13(10)11-5-3-2-4-6-11/h2-9H,14H2,1H3

Upstream product

• 620-25-7 N-(3-methylphenyl)hydroxylamine 
• 71-43-2 benzene 
• 539-44-6 N-4-methylphenylhydrazine 

Downstream Products

• 230961-37-2 (N₄,3S)-dihydroxy-N₁-[(1S)-2,2-dimethyl-1-({[(1S)-2-hydroxy-1-phenylethyl]amino}carbonyl)propyl]-(2R)-2-{3-[3-methyl-(4-phenyl)phenyl]propyl}butanediamide 
• 230961-31-6 (3R)-3-({({[(1S)-2-methoxy-1-phenylethyl]amino}carbonyl)-[(1S)-2-phenylethyl]amino}carbonyl)-6-[3-methyl-(4-phenyl)phenyl]hexanoic acid 
• 230962-00-2 (2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-[(3-methyl-4-phenyl)phenyl]pentanamide 
• 1359843-97-2 pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate 
• 1359843-95-0 pinacol(4-phenyl-3-(2-(tertbutylcarboxyl)ethyl)phenyl)boronate 

Relevant academic research and scientific papers

A TRIFLUOROMETHANESULFONIC ACID-CATALYZED REACTION OF ARYLHYDRAZINES WITH BENZENE

Arylhydrazines reacted with benzene in the presence of trifluoromethanesulfonic acid (TFSA) to give aminobiphenyls.This is a general method for the synthesis of aminobiphenyls.

Acid-Catalyzed Reactions of N-Arylhydroxylamines and Related Compounds with Benzene. Iminium-Benzenium Ions

N-Arylhydroxylamines react with benzene in the presence of trifluoroacetic acid (TFA) at room temperature to give diphenylamines.When TFA was replaced by a strong acid, trifluoromethanesulfonic acid (TFSA), the major products were aminobiphenyls.The nature of the reaction was explored by reactions of 4-substituted phenylhydroxylamines and dialkylaniline N-oxides with benzene.Thus, it was demonstrated that the reactive intermediates are onium-benzenium dications which are trapped by benzene to give aminobiphenyls by a mechanism similar to the Friedel-Krafts alkylation.Further evidence for the proposed reaction mechanism was the observation that nitrosobenzene and azoxybenzene reacted with benzene to give analogous products in the presence of the stronger acid.