63027-88-3

Basic information

• Product Name: 2,3,3-TRICHLOROTETRAHYDRO-2H-PYRAN
• Synonyms: 2H-Pyran,2,3,3-trichlorotetrahydro-;2,3,3-TRICHLOROTETRAHYDRO-2H-PYRAN;IMIDAZOLE-4(OR 5)-CARBOXYLIC ACID, 5(OR 4)-(3, 3-DIMETHYL-1-TRIAZENO)-, ETHYLESTER;2,3,3-Trichlorotetrahydro-2H-pyran,97%;2,3,3-trichlorooxane;2,3,3-trichlorotetrahydropyran
• CAS NO: 63027-88-3
• Molecular Formula: C5H7Cl3O
• Molecular Weight: 189.47
• Mol File: 63027-88-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 83 °C (11 mmHg)
• Flash Point: 96.9°C
• Appearance: /
• Density: 1.4
• Vapor Pressure: 0.0728mmHg at 25°C
• Refractive Index: 1.5051-1.5071
• CAS DataBase Reference: 2,3,3-TRICHLOROTETRAHYDRO-2H-PYRAN(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,3-TRICHLOROTETRAHYDRO-2H-PYRAN(63027-88-3)
• EPA Substance Registry System: 2,3,3-TRICHLOROTETRAHYDRO-2H-PYRAN(63027-88-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 63027-88-3(Hazardous Substances Data)

Usage

Chemical Properties

Clear colourless liquid

InChI:InChI=1/C5H7Cl3O/c6-4-5(7,8)2-1-3-9-4/h4H,1-3H2/t4-/m0/s1

Upstream product

• 142-68-7 TETRAHYDROPYRANE 
• 110-87-2 3,4-dihydro-2H-pyran 
• 111-29-5 1 ,5-pentanediol 

Downstream Products

• 141942-53-2 3,3-dichloro-2-formoxytetrahydropyran 
• 141942-54-3 2-acetoxy-3,3-dichlorotetrahydropyran 
• 76043-70-4 3,3-dichloro-2-hydroxytetrahydropyran 
• 141942-61-2 1,1,5-triacetoxy-2,2-dichloropentane 
• 141942-66-7 2,2-dichloro-1,5-pentanediol 

Relevant articles and documents

HIGH YIELD PREPARATION OF 2,3,3-TRICHLORINATED TETRAHYDROPYRAN WITH AN EXCESS OF REFLUXING SULFURYL CHLORIDE IN THE DARK

The chlorination of tetrahydropyran with an excess of refluxing sulfuryl chloride in the dark provided 2,3,3-trichlorotetrahydropyran in 94percent isolated yield, showing evidence for a very selective non-homolytic mechansims, probably involving hydride abstraction as the first step.

2,2-DICHLOROALDEHYDES FROM ALDEHYDES AND ALCOHOLS BY CHLORINATION IN DIMETHYLFORMAMIDE

A method is described for the synthesis of α,α-dichloroaldehydes, free from monochloroaldehyde, by chlorination of aldehydes or alcohols in dimethylformamide at 40-90 deg C.Results are reported for : (yield percent) propanal (90), butanal (78), pentanal (78), 3-methylbutanal (90), propanol (64), butanol (78), 3-methylbutanol (52), pentanol (66), 3,3-dimethylbutanol (86), hexanol (66), 2-phenylethanol (51), 3-phenylpropanol (54), 1,5-pentanediol , 1,6-hexanediol .Oxidative conversion (KMnO4, K2Cr2O7, H2O2-NaHCO3) into α,α-dichlorocarboxylic acids and methyl esters is discussed.