6303-66-8

Basic information

• Product Name: bicyclo[2.2.2]octane-7,8-dicarboxylic acid
• Synonyms: bicyclo[2.2.2]octane-7,8-dicarboxylic acid;Nsc42843
• CAS NO: 6303-66-8
• Molecular Formula: C10H14O4
• Molecular Weight: 198.22
• Mol File: 6303-66-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 414.3°C at 760 mmHg
• Flash Point: 218.5°C
• Appearance: /
• Density: 1.344g/cm³
• Vapor Pressure: 5.04E-08mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: bicyclo[2.2.2]octane-7,8-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: bicyclo[2.2.2]octane-7,8-dicarboxylic acid(6303-66-8)
• EPA Substance Registry System: bicyclo[2.2.2]octane-7,8-dicarboxylic acid(6303-66-8)

Safety Data

• Hazardous Substances Data: 6303-66-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H14O4/c11-9(12)7-5-1-2-6(4-3-5)8(7)10(13)14/h5-8H,1-4H2,(H,11,12)(H,13,14)

Upstream product

• 6537-90-2 (+/-)-5,7-dioxo-bicyclo[2.2.2]octane-2r,3c-dicarboxylic acid-anhydride 
• 84258-03-7 trans-Bicyclo<2.2.2>octen-(5)-2,3-dicarboxychlorid 
• 123-31-9 hydroquinone 
• 1165952-91-9 cyclohexa-1,3-diene 
• 7647-01-0 hydrogenchloride 
• 28871-77-4 cis-bicyclo[2.2.2]octane-dicarboxylic acid-(2.3) 
• 28871-80-9 bicyclo<2.2.2>oct-5-ene 2,3-endo,exo-dicarboxylic acid 

Relevant articles and documents

Enzymatic optical resolution of norbornanecarboxylic esters using Pig Liver Esterase

The hydrolysis of a series of norbornane-type carboxylic esters catalyzed by pig liver esterase (PLE) has been investigated.It was found that an exo-ester function (syn to the C7 methylene group) is hydrolyzed with high preference.Enantioselective hydrolysis can be accomplished when a vicinal carbonyl-containing function (ester, formyl, acetyl) is present in a trans position with respect to the exo ester.The regiospecifity of the enzymatic hydrolysis has been used for the separation of exo/endo mixtures of the cycloadducts derived from cyclopentadiene and alkene esters.The regiospecifity and enantioselectivity of the enzymatic hydrolysis of norbornane-type esters were analyzed in terms of Tamm's substrate model and also by Griengl's method.