63064-54-0

Upstream product

• 63064-49-3 allyl 2-acetamido-2-deoxy-4,6-O-benzylidene-α-D-glucopyranoside 
• 63064-51-7 allyl 2-acetamido-3-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 100-39-0 benzyl bromide 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 7512-17-6 N-Acetyl-D-glucosamine 
• 54400-75-8 allyl 2-acetamido-2-deoxy-α-D-glucopyranoside 

Downstream Products

• 71216-87-0 allyl O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-(1<*>3)-O-(2,4,6-tri-O-acetyl-β-D-mannopyranosyl)-(1<*>4)-O-(2-acetamido-3,6-di-O-acetyl-2-deoxy-β-D-glucopyranosyl)-(1<*>4)-2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 123809-58-5 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1→3)-1,2,4,6-tetra-O-acetyl-α,β-D-mannopyranose 
• 89067-90-3 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-α,β-D-glucopyranose 
• 82185-88-4 1,4-di-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-α,β-D-glucopyranose 
• 82185-92-0 allyl 2-acetamido-4-O-(4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 72333-25-6 allyl 3,4,6-tri-O-acetyl-2-(chloroacetamido)-2-deoxy-β-D-glucopyranoside 
• 129437-68-9 allyl O-(3,4,6-tri-O-acetyl-2-chloroacetamido-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 129437-72-5 allyl O-(3,4,6-tri-O-acetyl-2-chloroacetamido-2-deoxy-β-D-glucopyranosyl)-(1->4)-2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 705932-36-1 allyl 2-acetamido-2,4-dideoxy-3,6-di-O-benzyl-4-fluoro-α-D-galactopyranoside 
• 1221127-06-5 allyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-xylo-hexopyranoside-4-ulose 
• 705932-48-5 allyl 2-acetamido-2-deoxy-3,6-di-O-benzyl-4-mesyl-α-D-glucopyranoside 
• 63064-57-3 allyl O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-(1->4)-2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 92517-06-1 Acetic acid (2R,3S,4R,5R,6S)-6-((2R,3S,4R,5R,6S)-5-acetylamino-6-allyloxy-4-benzyloxy-2-benzyloxymethyl-tetrahydro-pyran-3-yloxy)-5-amino-4-benzyloxy-2-benzyloxymethyl-tetrahydro-pyran-3-yl ester 
• 65730-13-4 allyl 2-acetamido-4-O-(2-acetamido-4-O-acetyl-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranosyl)-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of amino-bridged oligosaccharide mimetics

Synthesis of amino-bridged oligosaccharides using reductive animation opens rapid access to novel glycomimetic target structures as potential ligands for the receptor protein NKR P1 of natural killer cells. Emphasis was laid on fast and facile synthetic routes. The carbonyl building blocks were easily obtained by oxidation with Dess-Martin periodinane or iodoxybenzoic acid (IBX). For the required amino-function-alized units, reduction of azide precursors was advantageous, and generation of the novel oligosaccharides was achieved by subsequent reductive amination. The target saccharide structures feature a bridging nitrogen atom inserted between two non-anomeric positions as well as including one anomeric position.

Chemo-enzymatic synthesis of fluorinated 2-N-acetamidosugar nucleotides using UDP-GlcNAc pyrophosphorylase.

Two non-natural fluorinated 2-N-acetamidosugar nucleotides, uridine 5'-diphosphate (UDP) 2-acetamido-2,4-dideoxy-4-fluoro-alpha-D-glucopyranose (UDP-4-FGlcNAc) 1 and its galacto isomer (UDP-4-FGalNAc) 2, were enzymatically constructed by treating chemical

Synthetic lipid A glycoconjugate antigens for use in vaccines

Synthetic glycoconjugate antigens of the formula: for use in vaccines for prophylaxis of septic shock caused by bacterial endotoxin and methods of preparing the glycoconjugates.

1,3,4,6-Tetra-O-acetyl-2-chloroacetamido-2-deoxy-β-D-glucopyranose as a glycosyl donor in syntheses of oligosaccharides

1,3,4,6-Tetra-O-acetyl-2-chloroacetamido-2-deoxy-β-D-glucopyranose was tested as a glycosyl donor for oligosaccharide synthesis via ferric chloride-catalyzed coupling reaction.Glycosyl acceptors tried (6 in all) were O-benzyl-protected D-galactosides having free OH groups at positions 3 and 4, respectively, and similarly protected glycosides of D-glucose and 2-acetamido-2-deoxy-D-glucose unsubstituted on O-4.Existing syntheses of all the acceptors were improved, in four instances by exploitation of Garegg and Hultberg's cyanoborohydride procedure for the conversion 4,6-O-benzylidene -> 6-O-benzyl .Good to excellent yields of β-linked disaccharides were obtained from the galactoside and glucoside acceptors, but with allyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside, stereoselectivity was lost (α:β-ratio 1:2).Allyl and benzyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranosides gave, respectively, the allyl and benzyl β-glycosides of the donor as major products.A mechanism is proposed for this transglycosidation reaction.The N-chloroacetyl groups in the disaccharide products were readily converted into N-acetyl by reduction with zinc-acetic acid.