6307-30-8

Usage

InChI:InChI=1/C12H16O3/c1-9-8-11(15-2)7-6-10(9)4-3-5-12(13)14/h6-8H,3-5H2,1-2H3,(H,13,14)

Upstream product

• 67405-48-5 4-(4-methoxy-2-methylphenyl)-4-oxo-but-1-oic acid 
• 127-09-3 sodium acetate 
• 73115-92-1 4-(4-Methoxy-2-methyl-phenyl)-butyric acid methyl ester 
• 77-78-1 dimethyl sulfate 
• 100-84-5 1-methoxy-3-methyl-benzene 

Downstream Products

• 19143-95-4 4-(4-hydroxy-2-methylphenyl)butanoic acid 
• 4693-98-5 4-<4-Methoxy-2-methyl-phenyl>-butanol-1 
• 19143-97-6 4-(4-Hydroxy-2-methyl-phenyl)-butanol-⁽¹⁾ 
• 19143-96-5 γ-(4-Hydroxy-2-methyl-phenyl)-buttersaeure-methylester 
• 89837-14-9 2-(2-Carboxy-ethyl)-5-methoxy-3-methyl-benzoic acid 
• 858459-45-7 (6-methoxy-8-methyl-[1]naphthyl)-acetic acid 

Relevant academic research and scientific papers

Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents

Catechol diethers that incorporate a 7-cyano-2-naphthyl substituent are reported as non-nucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs). Many of the compounds have 1-10 nM potencies toward wild-type HIV-1. An interesting conformational effect allows two unique conformers for the naphthyl group in complexes with HIV-RT. X-ray crystal structures for 4a and 4f illustrate the alternatives.

Synthesis based on cyclohexadienes: Part 16 - Synthesis of methyl 2,7-dimethyltricyclo1,5>undec-5-ene-6-carboxylates

Synthesis of methyl 2,7-dimethyltricyclo1,5>undec-5-en-6-carboxylates, the tricyclic skeleton present in (+)-allo-cedrol (1) is described using the Diels-Alder strategy.Thus, Birch reduction of the aromatic acid 8 gives 5, the methyl es

Synthesis of 4-Hydroxy-2-methylbenzoic Acid and Its Higher Homologues

Synthesis of 4-hydroxy-2-methylbenzoic acid (1a) and its higher homologues such as 4-hydroxy-2-methylphenylacetic acid (1b), 3-(4-hydroxy-2-methylphenyl)propanoic acid (1c) and 4-(4-hydroxy-2-methylphenyl)butanoic acid (1d) are described.

Preparation of 5-(2-Benzoyloxymethyl-4-methoxy)phenyl-2(5H)-furanone

5-Phenyl-2(5H)-furanone (11), 5-(2-methyl-4-methoxy)phenyl-2(5H)-furanone (16) and 5-(2-benzoyloxymethyl-4-methoxy)phenyl-2(5H)-furanone (6) have been prepared from γ-phenyl-γ-butyrolactone (9), γ-(2-methyl-4-methoxy)phenyl-γ-butyrolactone (14) and γ-(2-benzoyloxymethyl-4-methoxy)phenyl-γ-butyrolactone (4) respectively employing the method of Sharpless. 11 has been converted into 4-oxo-4-phenylbutanoic acid (7) on treatment with alkali.During the Wolff-Kishner reduction of 4-oxo-4-(2-methyl-2-methoxyphenyl)butanoic acid (12) the demethylated product 4-(2-methyl-4-hydroxy)phenylbutanoic acid (19) has also been obtained.