6307-30-8

Basic information

• Product Name: 4-(4-METHOXY-2-METHYL-PHENYL)-BUTYRIC ACID
• Synonyms: 4-(4-METHOXY-2-METHYL-PHENYL)-BUTYRIC ACID;ASINEX-REAG BAS 05230804;TIMTEC-BB SBB011200;2-(4-methoxy-2-methylphenyl)butanoic acid
• CAS NO: 6307-30-8
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.25
• Mol File: 6307-30-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 356.1°Cat760mmHg
• Flash Point: 135.2°C
• Appearance: /
• Density: 1.095g/cm³
• Vapor Pressure: 1.1E-05mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: 4-(4-METHOXY-2-METHYL-PHENYL)-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-METHOXY-2-METHYL-PHENYL)-BUTYRIC ACID(6307-30-8)
• EPA Substance Registry System: 4-(4-METHOXY-2-METHYL-PHENYL)-BUTYRIC ACID(6307-30-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 6307-30-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O3/c1-9-8-11(15-2)7-6-10(9)4-3-5-12(13)14/h6-8H,3-5H2,1-2H3,(H,13,14)

Upstream product

• 67405-48-5 4-(4-methoxy-2-methylphenyl)-4-oxo-but-1-oic acid 
• 77-78-1 dimethyl sulfate 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 127-09-3 sodium acetate 
• 73115-92-1 4-(4-Methoxy-2-methyl-phenyl)-butyric acid methyl ester 

Downstream Products

• 858459-45-7 (6-methoxy-8-methyl-[1]naphthyl)-acetic acid 
• 89837-14-9 2-(2-Carboxy-ethyl)-5-methoxy-3-methyl-benzoic acid 
• 4693-98-5 4-<4-Methoxy-2-methyl-phenyl>-butanol-1 
• 19143-95-4 4-(4-hydroxy-2-methylphenyl)butanoic acid 
• 19143-97-6 4-(4-Hydroxy-2-methyl-phenyl)-butanol-⁽¹⁾ 
• 19143-96-5 γ-(4-Hydroxy-2-methyl-phenyl)-buttersaeure-methylester 

Relevant articles and documents

Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents

Catechol diethers that incorporate a 7-cyano-2-naphthyl substituent are reported as non-nucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs). Many of the compounds have 1-10 nM potencies toward wild-type HIV-1. An interesting conformational effect allows two unique conformers for the naphthyl group in complexes with HIV-RT. X-ray crystal structures for 4a and 4f illustrate the alternatives.

Synthesis of 4-Hydroxy-2-methylbenzoic Acid and Its Higher Homologues

Synthesis of 4-hydroxy-2-methylbenzoic acid (1a) and its higher homologues such as 4-hydroxy-2-methylphenylacetic acid (1b), 3-(4-hydroxy-2-methylphenyl)propanoic acid (1c) and 4-(4-hydroxy-2-methylphenyl)butanoic acid (1d) are described.