6308-18-5Relevant academic research and scientific papers
Extended Release of Native Drug Conjugated in Polyketal Microparticles
Guo, Shutao,Nakagawa, Yoshiyuki,Barhoumi, Aoune,Wang, Weiping,Zhan, Changyou,Tong, Rong,Santamaria, Claudia,Kohane, Daniel S.
, p. 6127 - 6130 (2016)
Polyketals, which can be biodegradable, have good biocompatibility, and are pH-sensitive, could have broad applicability in drug delivery and other biomedical applications. However, facile synthesis of high molecular weight polyketals is challenging, and
Dehydrogenative ester synthesis from enol ethers and water with a ruthenium complex catalyzing two reactions in synergy
Kar, Sayan,Luo, Jie,Rauch, Michael,Diskin-Posner, Yael,Ben-David, Yehoshoa,Milstein, David
supporting information, p. 1481 - 1487 (2022/03/07)
We report the dehydrogenative synthesis of esters from enol ethers using water as the formal oxidant, catalyzed by a newly developed ruthenium acridine-based PNP(Ph)-type complex. Mechanistic experiments and density functional theory (DFT) studies suggest that an inner-sphere stepwise coupled reaction pathway is operational instead of a more intuitive outer-sphere tandem hydration-dehydrogenation pathway.
SYNTHESIS OF BICYCLO[2.2.2]OCTANE DERIVATIVES
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Paragraph 0083, (2019/05/02)
Provided is a process for the preparation of certain 1,4-bicyclo[2.2.2]octane derivatives. The new synthetic procedure involves treating 1,4-dimethylene cyclohexane with an oxidizing agent in the presence of a transition metal catalyst to afford an oxo-substituted bicyclo[2.2.2]octane species. This intermediate structure can then be further derivatized. The processes of this disclosure thus affords a novel and simplified means for the commercial production of a wide variety of bicyclo[2.2.2]octane derivatives.
SYNTHESIS OF BICYCLO(2.2.2)OCTANES
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Paragraph 0040, (2018/05/15)
Provided is a process for the preparation of certain 1,4- bicyclo[2.2.2]octane derivatives. The new synthetic procedure involves treating 1,4-dimethylene cyclohexane with an oxidizing agent in the presence of a transition metal catalyst comprising a palla
Synthesis and characterization of polycarbonates by melt phase interchange reactions of alkylene and arylene diacetates with alkylene and arylene diphenyl dicarbonates
Sweileh, Bassam A.,Al-Hiari, Yusuf M.,Kailani, Mohammad H.,Mohammad, Hani A.
experimental part, p. 3661 - 3682 (2010/09/08)
This work presents a new synthetic approach to aromatic and aliphatic polycarbonates by melt polycondensation of bisphenol A diacetates with alkylene- and arylenediphenyl dicarbonates. The diphenyl dicarbonates were prepared from phenyl chloroformate and
