6312-22-7

Usage

Physical form

White solid

Molecular weight

197.23 g/mol

Melting point

44-46°C

Usage

Precursor in the synthesis of various pharmaceuticals and organic compounds

Potential intermediate

Production of drugs

Controlled substance

In some regions due to potential for abuse

Effects

Stimulant and psychoactive when ingested or inhaled

Safety precautions

Handle and store with caution

Risks

Potential risks and potential for misuse

Responsible use

Importance of using 1-phenyl-2-(pyridin-4-yl)propan-1-one safely and responsibly.

Upstream product

• 1620-55-9 1-phenyl-2-(4-pyridinyl)ethanone 
• 74-88-4 methyl iodide 
• 86123-43-5 benzoic acid-(1-phenyl-2-[4]pyridyl-propenyl ester) 
• 93617-68-6 4-(1-Methyl-2-oxo-2-phenyl-ethyl)-4H-pyridine-1-carboxylic acid phenyl ester 
• 71831-59-9 2,6-Dimethyl-4'-(1-methyl-2-oxo-2-phenyl-ethyl)-4'H-[1,1']bipyridinyl-4-one 
• 110-86-1 pyridine 
• 100-43-6 4-vinylpyridine 
• 455-32-3 benzoyl fluoride 
• 93-55-0 1-phenyl-propan-1-one 
• 86123-36-6 benzoic acid-(1-phenyl-2-[4]pyridyl-vinyl ester) 
• 89318-24-1 4-(1-Methyl-2-oxo-2-phenyl-ethyl)-4H-pyridine-1-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 536-75-4 4-Ethylpyridine 

Relevant academic research and scientific papers

Nickel-Copper-Catalyzed Hydroacylation of Vinylarenes with Acyl Fluorides and Hydrosilanes

The hydroacylation of vinylarenes with acyl fluorides and hydrosilanes was enabled by a synergistic bimetallic Ni/Cu-catalytic system, giving access to the corresponding branched ketone products. The reaction takes place under mild conditions at 25–80 °C and tolerates base-sensitive functional groups such as methoxycarbonyl and acetoxy groups.

REGIOSELECTIVE ADDITION OF TITANIUM ENOLATES TO 1-ACYLPYRIDINIUM SALTS. A CONVENIENT SYNTHESIS OF 4-(2-OXOALKYL)PYRIDINES

Titanium enolates add to the 4-position of 1-phenoxycarbonylpyridinium salts to give 1,4-dihydropyridines; subsequent aromatization provides 4-(2-oxoalkyl)pyridines.

Structure-Activity Relationship Study of the Inhibition of Adrenal Cortical 11β-Hydroxylase by New Metyrapone Analogues

Metyrapone, 2-methyl-1,2-di-3-pyridil-1-propanone (1a), is a potent reversible inhibitor of the cytochrome P-450 11β-hydroxylase enzyme system (P-45011β) of the adrenal cortex.The structural features of the metyrapone molecule have been systema

REGIOSELECTIVE SYNTHESIS OF 4-(2-OXOALKYL)PYRIDINES VIA 1,4-DIHYDROPYRIDINE DERIVATIVES USING SILYL ENOL ETHERS AND PYRIDINIUM SALTS

Trimethylsilyl enol ethers (1) reacted with 1-ethoxycarbonylpyridinium chloride (3) at 4-position with high regioselectivity to afford 1-ethoxycarbonyl-4-(2-oxoalkyl)-1,4-dihydropyridines (4) in 42-87percent yields.When 2,2,2-trichloroethyl chloroformate

Synthetic Applications of N-N Linked Heterocycles. Part 8. Regiospecific Synthesis of 4-(α-Acylalkyl)pyridines by Attack of Lithium Enolates of Ketones γ to N-(2,6-Dimethyl-4-oxopyridin-1-yl)pyridinium Salts

The addition of N-(2,6-dimethyl-4-oxopyridin-1-yl)pyridinium salts (2) - (4) to lithium enolates (1) of ketones in tetrahydrofuran at low temperatures gives regiospecifically high yields of 1,4-dihydro-adducts (5) - (7).These are readily isolated and can be decomposed under free-radical conditions, also in high yield, to 4-(α-acylalkyl)pyridines (8) - (10).Unsymmetrical dialkyl ketones give a mixture of two isomeric products, the ratio depending upon reaction conditions and steric factors. αβ-Unsaturated ketones, however, give products resulting from reaction exclusively at the position α' to the carbonyl group.