63126-52-3

Basic information

• Product Name: (S,S)-(-)-2,3-DIHYDROXY-N,N,N',N'-TETRAMETHYLSUCCINAMIDE
• Synonyms: N,N,N',N'-TETRAMETHYL-D-TARTARAMIDE;(-)-N,N,N',N'-TETRAMETHYL-D-TARTARDIAMIDE;(-)-N,N,N',N'-TETRAMETHYL-D-TARTARIC ACID DIAMIDE;N,N,N',N'-TETRAMETHYL-D-TARTRAMIDE;(S,S)-(-)-2,3-DIHYDROXY-N,N,N',N'-TETRAMETHYLSUCCINAMIDE;(-)-D-Tartaric acid bis(dimethylamide), (S,S)-(-)-2,3-Dihydroxy-N,N,Nμ,Nμ-tetramethylsuccinamide;(-)-D-Tartaric acid bis(dimethylamide), (S,S)-(-)-2,3-Dihydroxy-N,N,Nμ,Nμ-tetramethylsuccinamide, (-)-N,N,Nμ,Nμ-Tetramethyl-D-tartaric acid diamide;(2S,3S)-2,3-Dihydroxy-N,N,N',N'-tetramethylbutanediamide
• CAS NO: 63126-52-3
• Molecular Formula: C₈H₁₆N₂O₄
• Molecular Weight: 204.22
• Mol File: 63126-52-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 186-188 °C(lit.)
• Boiling Point: 342.71°C (rough estimate)
• Flash Point: 198.6 °C
• Appearance: White crystalline powder
• Density: 1.2441 (rough estimate)
• Refractive Index: -46 ° (C=3, EtOH)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
• PKA: 11.79±0.20(Predicted)
• BRN: 4675378
• CAS DataBase Reference: (S,S)-(-)-2,3-DIHYDROXY-N,N,N',N'-TETRAMETHYLSUCCINAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S,S)-(-)-2,3-DIHYDROXY-N,N,N',N'-TETRAMETHYLSUCCINAMIDE(63126-52-3)
• EPA Substance Registry System: (S,S)-(-)-2,3-DIHYDROXY-N,N,N',N'-TETRAMETHYLSUCCINAMIDE(63126-52-3)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 63126-52-3(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

Uses

N,N,N'',N''-Tetramethyl-D-tartaramide is an intermediate in the synthesis of Diethyl D-(-)-Tartrate (D445045). Diethyl D-(-)-Tartrate is used as a chiral reagent in a host of chemical reactions, suhc as marin toxin and antitumor agent phorboxazole A, or asymmetric syntheses of S,S-dialkyl-substituted sulfoximines.

Upstream product

• 13811-71-7 diethyl (2S,3S)-tartrate 
• 124-40-3 dimethyl amine 
• 608-69-5 dimethyl meso-tartrate 
• 21066-72-8 diethyl tartrate 

Downstream Products

• 161344-84-9 (4S,5S)-2-butyl-N⁴,N⁴,N⁵,N⁵-tetramethyl-1,3,2-dioxaborolane-4,5-dicarboxamide 
• 111828-49-0 (S,S)-(-)-N,N,N',N'-tetramethyl-2,2-dimethyl-1,3-dioxolane-trans-4,5-dicarboxamide 

Relevant articles and documents

From single molecule to crystal: Mapping out the conformations of tartaric acids and their derivatives

Stereoisomers of one of the most important organic compounds, tartaric acid, optically active and meso as well as the ester or amide derivatives, can show diverse structures related to the rotation around the three carbon-carbon bonds. This study determin