63131-32-8

Upstream product

• 106-42-3 para-xylene 
• 36239-09-5 ethyl chlorocarbonylacetate 
• 623-73-4 diazoacetic acid ethyl ester 
• 5779-94-2 2,5-dimethylbenzaldehyde 

Downstream Products

• 63131-15-7 C₁₇H₂₅O₄PS 
• 63131-16-8 C₁₈H₂₇O₄PS₂ 
• 63131-14-6 C₁₈H₂₇O₃PS₂ 

Relevant academic research and scientific papers

MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, compositions containing such molecules, and processes of using such molecules and compositions against such pests. These molecules and compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula ("Formula One").

Acid-catalyzed reactions of aromatic aldehydes with ethyl diazoacetate: An investigation on the synthesis of 3-hydroxy-2-arylacrylic acid ethyl esters

Several commercial Lewis acids, including those of the Bronsted type, specifically HBF4·OEt2, are able to catalyze the reaction between aromatic aldehydes and ethyl diazoacetate to produce 3-hydroxy-2-arylacrylic acid ethyl esters and 3-oxo-3-arylpropanoic acid ethyl esters. Reactions catalyzed by the iron Lewis acid [(η5-C 5H5)Fe+(CO)2(THF)]BF 4- (i.e., 1) have the best yields and greatest ratio of 3-hydroxy-2-arylacrylic acid ethyl ester. The product distribution of 1 is not affected in the presence of Proton Sponge, but is dependent on temperature and the nature of the substrate aldehyde, whereas the activity of HBF 4-OEt2 is affected by the presence of Proton Sponge and is reactive at temperatures as low as -78 °C. Consequently, both 1 and HBF4·OEt2 are valuable catalysts in producing important 3-hydroxy-2-arylacrylic acid ethyl esters as precursors to biologically active compounds.