63132-74-1

Usage

Uses

Used in Chemical Synthesis:
N-(2-bromoethyl)methanesulfonamide is used as a reactive intermediate in chemical synthesis for its bromoethyl group, which can participate in various organic reactions, facilitating the creation of new compounds and molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, N-(2-bromoethyl)methanesulfonamide is utilized as a starting material or intermediate in the development of new drugs. Its antimicrobial properties and potential reactivity in chemical processes make it a valuable candidate for research into novel therapeutic agents.
Used in Antimicrobial Agents:
N-(2-bromoethyl)methanesulfonamide is used as an antimicrobial agent for its inherent ability to combat bacteria and fungi, leveraging the well-established antimicrobial properties of sulfonamides.
If further applications are identified in specific industries, they can be listed as follows:
Used in [Specific Application Industry]:
N-(2-bromoethyl)methanesulfonamide is used as [specific application type] for [specific application reason], highlighting its versatility and potential across various fields.

InChI:InChI=1/C3H8BrNO2S/c1-8(6,7)5-3-2-4/h5H,2-3H2,1H3

Upstream product

• 2576-47-8 2-bromoethylamine hydrobromide 
• 124-63-0 methanesulfonyl chloride 
• 107-09-5 2-bromoethylamine 

Downstream Products

• 1450604-06-4 C₁₉H₂₆N₂O₆S₂ 
• 71045-92-6 N-[2-(4-hydroxy-N-methyl-anilino)-ethyl]-methanesulfonamide 

Relevant academic research and scientific papers

Synthesis of C- and N-Substituted 1,5,2,6-Dithiadiazocanes –Electrophilic-Nucleophilic Thioamination (ENTA) Reagents

A synthetic method is presented for S?N bond formation starting from cheap and affordable materials. We show that (un)substituted N-protected cyclic eight-membered C2-symmetric sulfenamides have been prepared in a few steps using this procedure. The synthetic utility of these ambipolar derivatives was demonstrated in a variety of synthetic transformations affording different S,N-heterocyles of pharmaceutical relevance in one or two steps from simple starting materials. (Figure presented.).

Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection

The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5 and R6 are as described herein, compositions including the compounds and methods of using the compounds.

NOVEL DIHYDROQUINOLIZINONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The invention provides novel compounds having the general formula (I) wherein R1, R2 R3, R4, R5 and R6 are as described herein, compositions including the compounds and methods of using the compounds in the treatment of the hepatitis B virus.

HSP90 INHIBITORS

The disclosure relates to Compounds of Formulae (IA) and (IB), and pharmaceutically acceptable salts thereof wherein Z1, Z2, Z3, Xa, Xb, Xc, Xd, Y, X2, and X4 are as defined herein, compositions comprising an effective amount of a Compound of Formula (IA) and/or (IB), and methods to treat or prevent a condition, such cancer which overexpresses Her-kinases, comprising administering to an patient in need thereof a therapeutically effective amount of a Compound of Formula (IA) or (IB). The disclosure further relates to compounds of Formulae (IA) and (IB) in which X2 is a leaving for introducing a radiolabeled atom, such as 124I or 131I and to methods of using such compounds in the preparation of radiolabeled compounds, particularly for use in imaging.

NOVEL OXABISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS

There is provided compounds of formula I, wherein R1, R2, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

Triazaspiro compounds, particularly 8-(3,3-diphenylpropyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane derivatives, with opioid receptor stimulating activity, useful for treating or preventing pain.

Triazaspiro Compounds, compositions comprising a Triazaspiro Compound, methods for treating or preventing pain in an animal comprising administering to an animal in need thereof an effective amount of a Triazaspiro Compound and methods for stimulating opioid-receptor function in a cell comprising contacting a cell capable of expressing an opioid receptor with an effective amount of a Triazaspiro Compound are disclosed.

Practical Synthesis of Sultams via Sulfonamide Dianion Alkylation: Application to the Synthesis of Chiral Sultams

(Equation presented) A practical synthesis of sultams was developed via intramolecular sulfonamide dianion alkylation. This method has been applied toward the synthesis of chiral sultams, which are synthetically valuable as chiral auxiliaries.

CONDENSED INDOLE DERIVATIVES AS 5HT4-RECEPTOR ANTAGONISTS

Compounds of formula (I) and pharmaceutically acceptable salts thereof: STR1 and their use as pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.

Condensed indole derivatives as 5HT4 -receptor antagonists

Compounds of formula (I) and pharmaceutically acceptable salts thereof: STR1 and their use as pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.