63134-33-8

Basic information

• Product Name: 4-[(4-Benzyloxyphenyl)sulfonyl]phenol
• Synonyms: TIMTEC-BB SBB002944;-[[4-(phenylmethoxy)phenyl]sulfonyl]phenol;4-[[4-(phenylmethoxy)phenyl]sulfonyl]-pheno;4-BENZYLOXYPHENYL 4-HYDROXYPHENYL SULFONE;4-BENZYLOXYPHENYL-4'-HYDROXYPHENYLSULFONE;4-HYDROXY-4'-BENZYLOXY DIPHENYL SULFONE;p-[[p-benzyloxyphenyl]sulphonyl]phenol;4-benzyloxy-4-hydroxydiphenyl sulphone
• CAS NO: 63134-33-8
• Molecular Formula: C₁₉H₁₆O₄S
• Molecular Weight: 340.39
• EINECS: 263-920-3
• Mol File: 63134-33-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 170 °C
• Boiling Point: 558.6°C at 760 mmHg
• Flash Point: 291.6°C
• Appearance: /
• Density: 1.304g/cm³
• Vapor Pressure: 4.39E-13mmHg at 25°C
• Refractive Index: 1.63
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 7.23±0.15(Predicted)
• CAS DataBase Reference: 4-[(4-Benzyloxyphenyl)sulfonyl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-Benzyloxyphenyl)sulfonyl]phenol(63134-33-8)
• EPA Substance Registry System: 4-[(4-Benzyloxyphenyl)sulfonyl]phenol(63134-33-8)

Safety Data

• Hazardous Substances Data: 63134-33-8(Hazardous Substances Data)

Usage

General Description

4-[(4-Benzyloxyphenyl)sulfonyl]phenol is a chemical compound that is commonly used in organic synthesis and pharmaceutical research. It is a member of the sulfonamide family and contains a sulfonyl group, which makes it useful for the development of potential drugs. 4-[(4-Benzyloxyphenyl)sulfonyl]phenol has a phenol functional group and a benzyl ether group, making it versatile for use in various reactions and transformations. Its molecular structure and properties make it a valuable building block in the synthesis of various biologically active compounds, and it has the potential to be a key component in the development of new drugs and pharmaceuticals.

InChI:InChI=1/C19H16O4S/c20-16-6-10-18(11-7-16)24(21,22)19-12-8-17(9-13-19)23-14-15-4-2-1-3-5-15/h1-13,20H,14H2

Upstream product

• 80-09-1 4,4'-sulfonediphenol 
• 100-39-0 benzyl bromide 

Downstream Products

• 392743-68-9 benzene-1,3-dicarboxylic acid 4-{[4-(benzyloxy)phenyl]sulfonyl}phenyl benzyl diester 
• 392743-72-5 3-[(methylamino)carbonyl]benzoic acid 4-{[4-(benzyloxy)phenyl]sulfonyl}phenyl diester 
• 392743-73-6 3-[(methylamino)carbonyl]benzoic acid 4-[4-(hydroxyphenyl)sulfonyl]phenyl ester 
• 392743-70-3 benzene-1,3-dicarboxylic acid 4-{[4-(hydroxyphenyl)sulfonyl]phenyl} ester 
• 141420-50-0 2-methyl-2-[[4-[[4-(phenylmethoxy)phenyl]sulfonyl]phenoxy]methyl]-oxirane 
• 138482-71-0 4-benzyloxy-4'-glycidyloxydiphenyl-sulfone 
• 172970-73-9 4-(4-benzyloxyphenylsulfonyl)phenoxypinacolone 

Relevant articles and documents

AB-type monomers for the preparation of perfluorocycloalkene (PFCA) aryl ether polymers

A method for the preparation of AB-type monomers with complimentary fluoro-olefin and phenol functionalities is described. The three-step process is amenable to commercial scale up and uses widely-available, commercial reagents including bisphenols and perfluorocycloalkene (PFCA) compounds. Title compounds and intermediates were characterized via multi-nuclear NMR and FT-IR spectroscopy providing structural and mechanistic elucidation of PFCA step-growth polymerizations. The formation of vinyl and allyl substituted products were quantified and shown to be dependent on PFCA ring size and reaction medium. Nearly equal amounts of vinyl- and allyl-substituted products were observed with perfluorocyclohexene (PFCH) while 2-11% allyl-substitution was observed with perfluorocyclopentene (PFCP), depending on reaction medium polarity. Previous PFCA research and characterization of title compounds suggests that fluoride-catalyzed rearrangement is primarily responsible the formation of two substitution products. Polymerization of an AB-type monomer derived from bisphenol A is demonstrated and was shown to reproducibly result in film-forming polymers with higher molecular weights than previously described methods.

COLOR DEVELOPING COMPOSITION CONTAINING MOLECULAR COMPOUND, AND RECORDING MATERIAL

Provided is a color-developing composition containing a molecular compound which has as a component compound a compound represented by formula (I) [wherein Y represents a C1-C12 hydrocarbon group which is chained or branched and saturated or unsaturated, or a C1-C8 hydrocarbon group which is chained or branched, saturated or unsaturated and has an ether or thioether bond; R1, R2, R3 and R4 each independently represent a C1-C6 alkyl group or C2-C6 alkenyl group; n, p, q and r each represents any integer of 0 to 4; and m represents any integer of 0 to 2]. Also provided is a recording material with a sufficient color-forming sensitivity, superior storage stability, and especially with an extremely little background fogging in a heat resistance test.

Reactive immunization elicits catalytic antibodies for polyester hydrolysis

In the search for biocatalysts for degradation of nonnatural polymers, reactive immunization with haptens 7 and 11 was used to prepare catalytic antibodies capable of cleaving short oligomeric esters, as well as the insoluble polyester 25. These antibodies were found to be highly specific and efficient esterases for oligomers. Triester 24 was preferentially hydrolyzed by an endo-cleavage pathway, however, with a higher molecular weight polymer 25 no site specificity could be observed. Catalytic efficiency of the antibodies towards the insoluble polymer 25 was limited due to physical constraints.