63134-33-8

Usage

Uses

Used in Pharmaceutical Research:
4-[(4-Benzyloxyphenyl)sulfonyl]phenol is used as a building block for the development of potential drugs due to its versatile molecular structure and properties. Its sulfonyl group and phenol functional group enable it to participate in various reactions and transformations, making it a valuable component in the synthesis of biologically active compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 4-[(4-Benzyloxyphenyl)sulfonyl]phenol is used as a versatile intermediate for the synthesis of a wide range of chemical compounds. Its benzyl ether group allows for further functionalization and modification, making it a useful starting material for the preparation of various organic molecules.
Used in Drug Development:
4-[(4-Benzyloxyphenyl)sulfonyl]phenol is employed as a key component in the development of new drugs and pharmaceuticals. Its unique molecular structure and properties make it a promising candidate for the design and synthesis of novel therapeutic agents with potential applications in various medical fields.
Used in Medicinal Chemistry:
In medicinal chemistry, 4-[(4-Benzyloxyphenyl)sulfonyl]phenol is utilized as a structural motif for the design of new drug candidates. Its sulfonyl and phenol functional groups can be further modified to enhance the compound's biological activity and selectivity, making it a valuable tool for the development of targeted therapeutic agents.
Used in Chemical Libraries:
4-[(4-Benzyloxyphenyl)sulfonyl]phenol is incorporated into chemical libraries for high-throughput screening and drug discovery efforts. Its unique structural features and potential for further functionalization make it a valuable addition to compound collections, facilitating the identification of novel lead compounds and the exploration of new chemical space.

InChI:InChI=1/C19H16O4S/c20-16-6-10-18(11-7-16)24(21,22)19-12-8-17(9-13-19)23-14-15-4-2-1-3-5-15/h1-13,20H,14H2

Upstream product

• 80-09-1 4,4'-sulfonediphenol 
• 100-39-0 benzyl bromide 

Downstream Products

• 392743-68-9 benzene-1,3-dicarboxylic acid 4-{[4-(benzyloxy)phenyl]sulfonyl}phenyl benzyl diester 
• 141420-50-0 2-methyl-2-[[4-[[4-(phenylmethoxy)phenyl]sulfonyl]phenoxy]methyl]-oxirane 
• 138482-71-0 4-benzyloxy-4'-glycidyloxydiphenyl-sulfone 
• 172970-73-9 4-(4-benzyloxyphenylsulfonyl)phenoxypinacolone 
• 392743-70-3 benzene-1,3-dicarboxylic acid 4-{[4-(hydroxyphenyl)sulfonyl]phenyl} ester 
• 392743-73-6 3-[(methylamino)carbonyl]benzoic acid 4-[4-(hydroxyphenyl)sulfonyl]phenyl ester 
• 392743-72-5 3-[(methylamino)carbonyl]benzoic acid 4-{[4-(benzyloxy)phenyl]sulfonyl}phenyl diester 

Relevant academic research and scientific papers

AB-type monomers for the preparation of perfluorocycloalkene (PFCA) aryl ether polymers

A method for the preparation of AB-type monomers with complimentary fluoro-olefin and phenol functionalities is described. The three-step process is amenable to commercial scale up and uses widely-available, commercial reagents including bisphenols and perfluorocycloalkene (PFCA) compounds. Title compounds and intermediates were characterized via multi-nuclear NMR and FT-IR spectroscopy providing structural and mechanistic elucidation of PFCA step-growth polymerizations. The formation of vinyl and allyl substituted products were quantified and shown to be dependent on PFCA ring size and reaction medium. Nearly equal amounts of vinyl- and allyl-substituted products were observed with perfluorocyclohexene (PFCH) while 2-11% allyl-substitution was observed with perfluorocyclopentene (PFCP), depending on reaction medium polarity. Previous PFCA research and characterization of title compounds suggests that fluoride-catalyzed rearrangement is primarily responsible the formation of two substitution products. Polymerization of an AB-type monomer derived from bisphenol A is demonstrated and was shown to reproducibly result in film-forming polymers with higher molecular weights than previously described methods.

AB-type monomers for the preparation of perfluorocycloalkene (PFCA) aryl ether polymers

A method for the preparation of AB-type monomers with complimentary fluoro-olefin and phenol functionalities is described. The three-step process is amenable to commercial scale up and uses widely-available, commercial reagents including bisphenols and perfluorocycloalkene (PFCA) compounds. Title compounds and intermediates were characterized via multi-nuclear NMR and FT-IR spectroscopy providing structural and mechanistic elucidation of PFCA step-growth polymerizations. The formation of vinyl and allyl substituted products were quantified and shown to be dependent on PFCA ring size and reaction medium. Nearly equal amounts of vinyl- and allyl-substituted products were observed with perfluorocyclohexene (PFCH) while 2-11% allyl-substitution was observed with perfluorocyclopentene (PFCP), depending on reaction medium polarity. Previous PFCA research and characterization of title compounds suggests that fluoride-catalyzed rearrangement is primarily responsible the formation of two substitution products. Polymerization of an AB-type monomer derived from bisphenol A is demonstrated and was shown to reproducibly result in film-forming polymers with higher molecular weights than previously described methods.

COLOR DEVELOPING COMPOSITION CONTAINING MOLECULAR COMPOUND, AND RECORDING MATERIAL

Provided is a color-developing composition containing a molecular compound which has as a component compound a compound represented by formula (I) [wherein Y represents a C1-C12 hydrocarbon group which is chained or branched and saturated or unsaturated, or a C1-C8 hydrocarbon group which is chained or branched, saturated or unsaturated and has an ether or thioether bond; R1, R2, R3 and R4 each independently represent a C1-C6 alkyl group or C2-C6 alkenyl group; n, p, q and r each represents any integer of 0 to 4; and m represents any integer of 0 to 2]. Also provided is a recording material with a sufficient color-forming sensitivity, superior storage stability, and especially with an extremely little background fogging in a heat resistance test.

Thermosensitive recording material and color developer compound therefor

A thermosensitive recording material has a support and a thermosensitive coloring layer formed thereon containing a leuco dye and a color developer capable of inducing color formation in the leuco dye upon application of heat thereto, with the color developer including at least one compound (A) having in a molecule thereof at least two aromatic ring moieties with specific structures, selected from the group consisting of an aromatic ring moiety having at least one carboxyl group and electron-attracting functional group, an aromatic ring moiety having at least one carboxyl group and electron-donating functional group, and an aromatic ring moiety having at least one carboxyl group, free of the electron-attracting and electron-donating functional groups. An aromatic carboxylic acid compound serving as the above-mentioned compound (A) and the producing method thereof are also disclosed.

Reactive immunization elicits catalytic antibodies for polyester hydrolysis

In the search for biocatalysts for degradation of nonnatural polymers, reactive immunization with haptens 7 and 11 was used to prepare catalytic antibodies capable of cleaving short oligomeric esters, as well as the insoluble polyester 25. These antibodies were found to be highly specific and efficient esterases for oligomers. Triester 24 was preferentially hydrolyzed by an endo-cleavage pathway, however, with a higher molecular weight polymer 25 no site specificity could be observed. Catalytic efficiency of the antibodies towards the insoluble polymer 25 was limited due to physical constraints.

Phenolic compounds

A phenolic compound having formula (I): STR1 wherein X represents a chlorine atom or a methyl group, and a recording material comprising a coloress or light-colored leuco dye and the above phenolic compound serving as a color developer for the leuco dye are disclosed.