63139-16-2 Usage
Uses
Used in Pharmaceutical Industry:
Withanolides are used as therapeutic agents for their anti-inflammatory, antioxidant, and immunomodulatory effects. They are particularly studied for their potential in reducing stress, anxiety, and fatigue, as well as their potential in cancer treatment and anti-aging effects.
Used in Neurodegenerative Disease Treatment:
Withanolides are used as neuroprotective agents for their potential to improve cognitive function and enhance memory and learning abilities. They are being researched for their potential applications in treating neurodegenerative diseases and stress-related disorders.
Used in Stress-Related Disorders:
Withanolides are used as stress-relief agents for their ability to reduce stress, anxiety, and fatigue. They are being studied for their potential applications in managing stress-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 63139-16-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,1,3 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 63139-16:
(7*6)+(6*3)+(5*1)+(4*3)+(3*9)+(2*1)+(1*6)=112
112 % 10 = 2
So 63139-16-2 is a valid CAS Registry Number.
InChI:InChI=1/C28H40O8/c1-15-13-21(36-22(31)16(15)2)25(5,32)28(35)12-11-26(33)18-14-20(30)27(34)9-6-7-19(29)24(27,4)17(18)8-10-23(26,28)3/h6-7,17-18,20-21,30,32-35H,8-14H2,1-5H3
63139-16-2Relevant academic research and scientific papers
Synthetic Modifications of Withanolides with an α-Orientated Side-Chain
Glotter, Erwin,Kumar, Sandeep,Sahai, Mahendra,Goldman, Alex,Kirson, Isaac,Mendelovici, Marioara
, p. 739 - 745 (2007/10/02)
In view of the antitumour activity of withanolide E and 4β-hydroxywithanolide E, synthetically modified analogues were prepared.In these compounds, the α-orientation of the side-chain was retained.Its degree of bending with respect to the carbocyclic skeleton depends on the presence or absence of the 14α-OH group.Elimination of this group leads to the formation of the 14,20-oxido-bridged and Δ14-compounds.Epoxidation of the latter afforded 14α,15α-epoxides.With the exception of several 5,6-chlorohydrins, most compounds possess an epoxide ring, allylic or homoallylic with respect to the ring A enone.
