108030-78-0

Basic information

• Product Name: Ergosta-2,24-dien-26-oicacid, 5-chloro-6,14,17,20,22-pentahydroxy-1-oxo-, d-lactone, (5a,6b,17a,22R)-
• Synonyms: WithanolideC
• CAS NO: 108030-78-0
• Molecular Formula: C28H39 Cl O7
• Molecular Weight: 523.066
• Mol File: 108030-78-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ergosta-2,24-dien-26-oicacid, 5-chloro-6,14,17,20,22-pentahydroxy-1-oxo-, d-lactone, (5a,6b,17a,22R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ergosta-2,24-dien-26-oicacid, 5-chloro-6,14,17,20,22-pentahydroxy-1-oxo-, d-lactone, (5a,6b,17a,22R)-(108030-78-0)
• EPA Substance Registry System: Ergosta-2,24-dien-26-oicacid, 5-chloro-6,14,17,20,22-pentahydroxy-1-oxo-, d-lactone, (5a,6b,17a,22R)-(108030-78-0)

Safety Data

• Hazardous Substances Data: 108030-78-0(Hazardous Substances Data)

Upstream product

• 38254-15-8 (+)-withanolide E 

Downstream Products

• 63139-16-2 withanolide S 
• 38254-15-8 (+)-withanolide E 
• 81644-34-0 withaperuvin C 

Relevant articles and documents

Synthetic Modifications of Withanolides with an α-Orientated Side-Chain

In view of the antitumour activity of withanolide E and 4β-hydroxywithanolide E, synthetically modified analogues were prepared.In these compounds, the α-orientation of the side-chain was retained.Its degree of bending with respect to the carbocyclic skeleton depends on the presence or absence of the 14α-OH group.Elimination of this group leads to the formation of the 14,20-oxido-bridged and Δ14-compounds.Epoxidation of the latter afforded 14α,15α-epoxides.With the exception of several 5,6-chlorohydrins, most compounds possess an epoxide ring, allylic or homoallylic with respect to the ring A enone.