63169-61-9

Basic information

• Product Name: 2-METHYLPENTANOIC ANHYDRIDE
• Synonyms: 2-METHYLPENTANOIC ANHYDRIDE;2-Methylpentanoic anhydride (2-Methylvaleric anhydride);2-METHYLPENTANOIC ANHYDRIDE 2-METHYLVALERIC ANHYDRIDE;Bis(2-methylpentanoic)anhydride
• CAS NO: 63169-61-9
• Molecular Formula: C₁₂H₂₂O₃
• Molecular Weight: 214.3
• Mol File: 63169-61-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 244.9°C at 760 mmHg
• Flash Point: 106.9°C
• Appearance: /
• Density: 0.94g/cm³
• Vapor Pressure: 0.0296mmHg at 25°C
• Refractive Index: 1.433
• CAS DataBase Reference: 2-METHYLPENTANOIC ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLPENTANOIC ANHYDRIDE(63169-61-9)
• EPA Substance Registry System: 2-METHYLPENTANOIC ANHYDRIDE(63169-61-9)

Safety Data

• Hazardous Substances Data: 63169-61-9(Hazardous Substances Data)

Usage

General Description

2-Methylpentanoic anhydride is a chemical compound with the molecular formula C7H12O3. It is an anhydride derivative of 2-methylpentanoic acid and is commonly used as a reagent in organic synthesis and in the production of pharmaceuticals. The compound is a colorless liquid with a pungent odor and is highly reactive, particularly in the presence of moisture. It is flammable and may cause irritation to the skin, eyes, and respiratory system upon exposure. Its main applications include as a precursor in the production of various chemicals and as a reagent in organic synthesis.

InChI:InChI=1/C12H22O3/c1-5-7-9(3)11(13)15-12(14)10(4)8-6-2/h9-10H,5-8H2,1-4H3

Upstream product

• 97-61-0 2-Methylpentanoic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 35900-26-6 4-Methyl-5-nonanone 
• 25218-64-8 4,4-Dimethyl-pentanoic acid [3-(2-methyl-pentanoylamino)-phenyl]-amide 
• 25228-85-7 2-Methyl-pentanoic acid (3-phenylacetylamino-phenyl)-amide 

Relevant articles and documents

PROCESSES FOR PREPARING 4-METHYL-5-NONANONE AND 4-METHYL-5-NONANOL

The present invention provides a process for preparing 4-methyl-5-nonanone of the following formula (3): the process comprising at least a step of subjecting 2-methylpentanoic anhydride of the following formula (1) and an n-butyl nucleophilic reagent of the following general formula (2) in which M represents Li, MgZ1, or ZnZ1, wherein Z1 represents a halogen atom or an n-butyl group, to a nucleophilic substitution. reaction Coproduce 4-methyl-5-nonanone (3), as well as a process for preparing 4-methyl-5-nonanol of the following formula (5), the process comprising at least steps of preparing 4-methyl-5-nonanone; and subjecting the obtained 4-methyl-5-nonanone and a reducing agent to a reduction reaction to produce 4-methyl-5-nonanol (5).

Friedel-Crafts Reaction of 2-Methylfuran with Saturated and α,β-Unsaturated Acid Anhydrides

2-Methylfuran (5) reacts with the saturated acid anhydrides 16 - 26 in the presence of SnCl4 to give the 2-acyl-5-methylfurans 37 - 47 selectively.The unsaturated anhydrides 27 - 32, however, yield mixtures which only in the case of senecioic acid anhydride (29) contain the respective primary product 48.Subsequent reactions lead to the addition products 55 (from 27) and 56 (from 29), and to (E,Z)-mixtures of their enol esters 57 - 62 which could partially be separated and assigned. - The olfactory properties of 2, 37 - 48, 50, 52, and 53 were investigated.