6317-65-3Relevant academic research and scientific papers
Efficient nickel/N-heterocyclic carbene catalyzed C-S cross-coupling
Guan, Pei,Cao, Changsheng,Liu, Yun,Li, Yunfei,He, Pan,Chen, Qian,Liu, Gang,Shi, Yanhui
supporting information, p. 5987 - 5992,6 (2012/12/12)
The cross-coupling reaction of aryl halides with aliphatic and aromatic thiols catalyzed by readily available Ni(OAc)2 with N-heterocyclic carbene (NHC) is reported. Ni(OAc)2/NHC catalyst showed good activities toward various aryl halides in C-S coupling reaction, even with aryl chlorides. Reactions occurred in excellent yields, broad scope, and high tolerance of functional groups.
Efficient nickel/N-heterocyclic carbene catalyzed C-S cross-coupling
Guan, Pei,Cao, Changsheng,Liu, Yun,Li, Yunfei,He, Pan,Chen, Qian,Liu, Gang,Shi, Yanhui
supporting information, p. 5987 - 5992 (2013/01/13)
The cross-coupling reaction of aryl halides with aliphatic and aromatic thiols catalyzed by readily available Ni(OAc)2 with N-heterocyclic carbene (NHC) is reported. Ni(OAc)2/NHC catalyst showed good activities toward various aryl halides in C-S coupling reaction, even with aryl chlorides. Reactions occurred in excellent yields, broad scope, and high tolerance of functional groups.
Carbon-sulfur coupling reactions catalyzed by Pd-NHC complex
Shi, Yanhui,Cai, Zhengyuan,Guan, Pei,Pang, Guangsheng
supporting information; experimental part, p. 2090 - 2096 (2011/10/09)
The cross-coupling reaction of aryl halides with aliphatic or aromatic thiols catalyzed by (SIPr)Pd(Py)Clis reported. This Pd-N-heterocyclic carbene (NHC) complex shows good to excellent activities toward various deactivated electron-rich aryl halides and even with unactivated aryl chlorides in C-S coupling reactions. The reactions proceeded in good yields, broad scope, and high tolerance of functional groups. The Pd-NHC complex is stable and easily to synthesize, so it is an excellent candidate to replace Pd-organophosphanes commonly used in C-S coupling catalysis. Georg Thieme Verlag Stuttgart - New York.
Diphenyl sulfoxides as selective antagonists of the muscarinic M2 receptor
Kozlowski, Joseph A,Lowe, Derek B.,Guzik, Henry S.,Zhou, Guowei,Ruperto, Vilma B.,Duffy, Ruth A.,McQuade, Robert,Crosby Jr., Gordon,Taylor, Lisa A.,Billard, William,Binch III, Herbert,Lachowicz, Jean E.
, p. 2255 - 2257 (2007/10/03)
Structure-activity studies on [4-(phenylsulfonyl)phenyl]methylpiperazine led to the discovery of 4-cyclohexyl-α-[4-[[4-methoxyphenyl](S)-sulfinyl]phenyl]-1-piperazineacetoni trile, 1, an M2 selective muscarinic antagonist. Affinity at the cloned human M2 receptor was 2.7 nM; the M1/M2 selectivity is 40-fold. (C) 2000 Elsevier Science Ltd.
