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6318-55-4

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6318-55-4 Usage

Uses

cis-Aconitic anhydride is used in the preparation of poly(amino acid)-containing copolymers with gradient pH-sensitive side groups initiated by the amino groups in methoxy poly(ethylene glycol)-block-poly(L-lysine). It is also involved in the preparation of pH-sensitive anti-tumor prodrug nanoparticles by conjugation with D-alfa-tocopheryl polyethylene glycol 1000 succinate (TPGS).

Purification Methods

Reflux it in xylene (7.5 parts) for 1hour, then evaporate and recrystallise the residue from *C6H6. Alternatively, reflux it in Ac2O, evaporate and recrystallise from *C6H6. It is sensitive to moisture. [IR: Groth & Dahlén Acta Chem Scand 21 291 1967, Malachowski & Maslowski Chem Ber 61 2523 1928, NMR: Gawron & Mahajan Biochemistry 5 2335 1966.] [Beilstein 18/8 V 530.]

Check Digit Verification of cas no

The CAS Registry Mumber 6318-55-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,1 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6318-55:
(6*6)+(5*3)+(4*1)+(3*8)+(2*5)+(1*5)=94
94 % 10 = 4
So 6318-55-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H6O5/c7-4(8)1-3-2-5(9)11-6(3)10/h3H,1-2H2,(H,7,8)

6318-55-4 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A16006)  cis-Aconitic anhydride, 98%   

  • 6318-55-4

  • 1g

  • 377.0CNY

  • Detail
  • Alfa Aesar

  • (A16006)  cis-Aconitic anhydride, 98%   

  • 6318-55-4

  • 5g

  • 1605.0CNY

  • Detail
  • Alfa Aesar

  • (A16006)  cis-Aconitic anhydride, 98%   

  • 6318-55-4

  • 25g

  • 6825.0CNY

  • Detail
  • Aldrich

  • (217808)  cis-Aconiticanhydride  95%

  • 6318-55-4

  • 217808-1G

  • 624.78CNY

  • Detail
  • Aldrich

  • (217808)  cis-Aconiticanhydride  95%

  • 6318-55-4

  • 217808-5G

  • 2,163.33CNY

  • Detail

6318-55-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2,5-dioxofuran-3-yl)acetic acid

1.2 Other means of identification

Product number -
Other names cis-acotinic anyhydride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6318-55-4 SDS

6318-55-4Relevant articles and documents

Competitive reactions during amine addition to cis-aconityl anhydride

Dinand, Elisabeth,Zloh, Mire,Brocchini, Steve

, p. 467 - 474 (2007/10/03)

Amine addition to cis-aconityl anhydride has been used to prepare monomers needed to make water-soluble polymers that are being developed for biomedical applications. Unfortunately competitive decarboxylation, double bond isomerization, and hydrolysis rea

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