6318-71-4 Usage
Uses
Used in Organic Synthesis:
[4-(2-Pyridin-2-ylethyl)phenyl]amine dihydrochloride is used as a building block in organic synthesis for the creation of various organic compounds. Its unique structure and reactivity allow for the formation of diverse chemical entities, contributing to the advancement of chemical research and development.
Used in Pharmaceutical Research:
In pharmaceutical research, [4-(2-Pyridin-2-ylethyl)phenyl]amine dihydrochloride is utilized as a key component in the synthesis of drugs. Its structural features and chemical properties make it a promising candidate for the development of new medications with potential therapeutic applications.
Used in Medication Development:
[4-(2-Pyridin-2-ylethyl)phenyl]amine dihydrochloride is employed in the development of new medications due to its potential to form bioactive molecules. Its unique structural elements and chemical reactivity enable the creation of compounds with specific therapeutic properties, broadening the scope of available treatments for various medical conditions.
Used in Bioactive Molecule Synthesis:
[4-(2-PYRIDIN-2-YLETHYL)PHENYL]AMINE DIHYDROCHLORIDE is also used in the synthesis of bioactive molecules, which can have significant impacts on biological systems. The ability of [4-(2-Pyridin-2-ylethyl)phenyl]amine dihydrochloride to form diverse chemical entities makes it a valuable asset in the discovery and production of bioactive substances with potential applications in medicine and other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 6318-71-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,1 and 8 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6318-71:
(6*6)+(5*3)+(4*1)+(3*8)+(2*7)+(1*1)=94
94 % 10 = 4
So 6318-71-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H14N2/c14-12-7-4-11(5-8-12)6-9-13-3-1-2-10-15-13/h1-5,7-8,10H,6,9,14H2
6318-71-4Relevant academic research and scientific papers
Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus
Kyei-Baffour, Kwaku,Mohammad, Haroon,Seleem, Mohamed N.,Dai, Mingji
, p. 1845 - 1854 (2019/03/28)
Antibiotic resistance remains a major global public health threat that requires sustained discovery of novel antibacterial agents with unexploited scaffolds. Structure-activity relationship of the first-generation aryl isonitrile compounds we synthesized led to an initial lead molecule that informed the synthesis of a second-generation of aryl isonitriles. From this new series of 20 compounds, three analogues inhibited growth of methicillin-resistant Staphylococcus aureus (MRSA) (from 1 to 4 μM) and were safe to human keratinocytes. Compound 19, with an additional isonitrile group exhibited improved activity against MRSA compared to the first-generation lead compound. This compound emerged as a candidate worthy of further investigation and further reinforced the importance of the isonitrile functionality in the compounds’ anti-MRSA activity. In a murine skin wound model, 19 significantly reduced the burden of MRSA, similar to the antibiotic fusidic acid. In summary, 19 was identified as a new lead aryl isonitrile compound effective against MRSA.
Studies on antiulcer drugs. V. Synthesis and antiulcer activity of aralkylbenzazoles
Katsura,Inoue,Tomoi,Takasugi
, p. 2062 - 2074 (2007/10/02)
A series of 2-alkylamino-5- or 6-aralkyl-substituted benzazoles were synthesized and tested for histamine H2-receptor antagonist and anti-stress ulcer activities. These new compounds showed little or no histamine H2-receptor antagoni
