631873-94-4

Basic information

• Product Name: 1H-Imidazole, 1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy](4-methoxyphenyl)methyl]-
• CAS NO: 631873-94-4
• Molecular Formula: C17H26N2O2Si
• Molecular Weight: 318.491
• Mol File: 631873-94-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy](4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy](4-methoxyphenyl)methyl]-(631873-94-4)
• EPA Substance Registry System: 1H-Imidazole, 1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy](4-methoxyphenyl)methyl]-(631873-94-4)

Safety Data

• Hazardous Substances Data: 631873-94-4(Hazardous Substances Data)

Upstream product

• 288-32-4 1H-imidazole 
• 123-11-5 4-methoxy-benzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 123-11-5 4-methoxy-benzaldehyde 
• 6013-92-9 1-(4-methoxyphenyl)-2,2-dimethylpropan-1-ol 
• 3319-15-1 rac-1-(4-methoxyphenyl)-ethanol 

Relevant articles and documents

Tuning the reactivity of O-tert-butyldimethylsilylimidazolyl aminals towards organolithium reagents

O-tert-Butyldimethylsilylimidazolyl aminals are N,O-acetals that form readily from aldehydes, and although they function as aldehyde stabilizing and protecting groups under various conditions, we report here that they react with organolithium reagents similarly to the parent aldehydes. The mechanism involves the intermediate formation of a 2-imidazolyl anion as is exemplified by the isolation of 2-TBDMS-imidazole. Substitution of the imidazolyl moiety at the 2-position renders these aldehyde derivatives stable to organolithium reagents, thus allowing for the tuning of their reactivity.