63190-87-4

Upstream product

• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 58905-32-1 3,3-dimethyl-1-(1,2,4-triazol-1-yl)-2-butanone 
• 622-95-7 4-chlorobenzyl bromide 
• 5469-26-1 1-Bromopinacolon 
• 75-97-8 3,3-dimethyl-butan-2-one 

Downstream Products

• 66345-53-7 paclobutrazol 
• 66346-05-2 Caswell No. 628C 
• 124339-88-4 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-one 

Relevant academic research and scientific papers

Preparation method of chlorenone

The invention relates to a preparation method of chlorenone. The chlorenone is prepared from 3, 3-dimethyl-1-(1H-1, 2, 4-triazole-1-yl) butane-2-one and p-chlorobenzyl chloride as raw materials through reaction, the reaction is carried out in the presence of a solvent, a catalyst and alkali, and the solvent is one or more of cyclohexane, isopropanol, n-butyl alcohol, toluene, methylcyclohexane andn-hexane. The method is relatively safe in process, simple to operate, low in cost, relatively high in target product content and yield, less in three wastes and suitable for industrial production.

New lead compounds for brassinosteroid biosynthesis inhibitors

The first brassinosteroid biosynthesis inhibitor is reported. Among newly synthesized triazole derivatives, 4-(4-chlorophenyl)-2-phenyl-3- (1,2,4-triazoyl)butan-2-ol (6) was found to inhibit the growth of cress seedlings, and this inhibition was recovered by the treatment of brassinolide, suggesting that compound 6 primarily inhibits brassinosteroid biosynthesis.

Fungicidal hydroxyalkinyl-azolyl derivatives

Hydroxyalkinyl-azolyl derivatives of the formula STR1 in which A is a nitrogen atom or the CH group, R is optionally substituted alkyl, cycloalkyl or phenyl, R1 is hydrogen, alkyl, alkenyl, alkinyl, or optionally substituted benzyl, R2 is hydrogen or methyl, and X is hydrogen, bromine or iodine, or addition products thereof with acids or metal salts exhibit fungicidal activity. Some intermediates therefor are also new.