66345-53-7

Usage

Uses

Used in Pharmaceutical Industry:
Isavuconazonium sulfate is used as an antifungal agent for the treatment of invasive aspergillosis and invasive mucormycosis. Its application is based on its ability to inhibit the growth of fungi by interfering with the synthesis of ergosterol, leading to the death of the fungus. It is available in both intravenous and oral formulations, making it a valuable option for treating serious fungal infections.

Upstream product

• 63190-87-4 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-one 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 58905-32-1 3,3-dimethyl-1-(1,2,4-triazol-1-yl)-2-butanone 
• 66346-01-8 1-(4-chlorophenyl)-4,4-dimethyl-pentan-3-one 
• 109-65-9 1-bromo-butane 
• 693-03-8 n-butyl magnesium bromide 
• 66346-00-7 α-(1,2,4-triazol-1-yl)-α-p-chlorobenzylchloride 
• 5469-26-1 1-Bromopinacolon 

Relevant academic research and scientific papers

New lead compounds for brassinosteroid biosynthesis inhibitors

The first brassinosteroid biosynthesis inhibitor is reported. Among newly synthesized triazole derivatives, 4-(4-chlorophenyl)-2-phenyl-3- (1,2,4-triazoyl)butan-2-ol (6) was found to inhibit the growth of cress seedlings, and this inhibition was recovered by the treatment of brassinolide, suggesting that compound 6 primarily inhibits brassinosteroid biosynthesis.

Patch preparations for treating plants

The following invention introduces a patch preparation for treating plants, whereas the patch preparations comprise a chemical layer composed of at least one agrochemically active compound, at least one adhesive and optionally, one or more additives. The components are dispersed in a matrix state on a substrate which are then introduced on the roots of the plant to be treated.

Method for the treatment of plants with agrochemical tablet compositions

Novel method for applying agrochemicals to plants, which method consists in attaching to the surface of the plants tablets comprising at least one agrochemically active compound and at least one adjuvant, which is solid, liquid of pasty at room temperature, and optionally, one or more excipients optionally in admixture with one or more other additives and/or water.

Use of diphenyl ether derivatives for the desiccation and abscission of plant organs

The use of diphenyl ether derivatives of the general formula I STR1 where A is a radical STR2 where R1 is hydrogen, an alkali metal or alkaline earth metal ion, substituted or unsubstituted ammonium, alkyl of from 1 to 4 carbon atoms or alkoxycarbonylalkyl of a total of 1 to 6 carbon atoms and R2 is alkyl of from 1 to 4 carbon atoms, for the desiccation and abscission of plant organs.

Combating fungi with triazolyl-benzyloxy-ketones and-carbinols

Triazolyl-benzyloxy-ketones or carbinols of the formula STR1 in which A is a keto group or a CH(OH) group, X is a halogen atom or an alkyl or halogenoalkyl radical, and n is 0, 1, 2, 3, 4 or 5, or an addition product thereof with a physiologically acceptable acid or metal salt, which possess fungicidal properties. Intermediates wherein A is a keto group and the azole group is replaced by chloride or bromine are also new.

Fungicidal compounds

Triazoles of formula: STR1 wherein R1 is alkenyl, alkynyl or optionally substituted aralkyl; Y is =N--, R2 is cycloalkyl, alkyl or haloalkyl, and R3 is H, methyl or alkenyl, or esters, ethers, salts and metal complexes thereof. The triazoles have fungicidal and plant growth regulating activity.