63235-14-3Relevant academic research and scientific papers
Synthesis of a pyrimidine isostere of the N-methyl-D-aspartate antagonist SDZ EAB 515
Chengzhi,Buechler,Lowe,Urwyler,Shapiro
, p. 5735 - 5740 (1994)
The synthesis of a pyrimidine isostere 2 of the potent N-methyl-D-aspartate (NMDA) receptor antagonist SDZ EAB 515, 1, has been achieved. Suprisingly, isostere 2 is more than two orders of magnitude less active than 1.
