63235-31-4

Upstream product

• 104-94-9 4-methoxy-aniline 
• 931-59-9 benzenesulfenyl chloride 
• 108-98-5 thiophenol 

Downstream Products

• 1212-08-4 S-Phenyl benzenethiosulfonate 
• 5051-19-4 2,7-dimethoxyphenazine 
• 100033-67-8 N-(p-methoxyphenyl)-N'-phenylthio-p-benzoquinone di-imine 
• 88047-06-7 N-phenylbis(benzenesulphen)amide 
• 104-94-9 4-methoxy-aniline 
• 882-33-7 diphenyldisulfane 
• 85695-73-4 N-(p-methoxyphenyl)bis(benzenesulphen)amide 
• 501-58-6 (E)-1,2-bis(4-methoxyphenyl)diazene 
• 100033-67-8 N-(4-methoxyphenyl)-N'-phenylthio-p-benzoquinone di-imine 
• 77134-91-9 N-(2-(phenylthio)cyclohexyl)acetamide 
• 115011-52-4 N--N'-(4-methoxyphenyl)acetamidine 
• 115011-48-8 (4-Methoxy-phenyl)-(2-phenylsulfanyl-cyclohexyl)-amine 
• 91525-60-9 trans-1-(phenylthio)-2-(4-methoxyphenylamino)cyclohexane 
• 14032-04-3 trans-2-phenylthiocyclohexanol 

Relevant academic research and scientific papers

Nitroarylamines via the Vicarious Nucleophilic Substitution of Hydrogen: Amination, Alkylamination, and Arylamination of Nitroarenes with Sulfenamides

A new reaction of sulfenamides with electrophilic arenes under basic conditions is described. The σ adducts formed from nitroarenes and the anions of sulfenamides undergo elimination of thiol to produce the corresponding o- and/or p-nitroanilines. This reaction is analogous to the known alkylation and hydroxylation of nitroarenes via the vicarious nucleophilic substitution of hydrogen (VNS). The reaction gives access to a wide range of substituted nitroanilines, nitronaphthylamines, and aminoheterocycles. By means of the reaction with N-alkyl- and N-arylsulfenamides, it is possible to obtain N-alkylnitroanilines and nitrodiarylamines. By varying the structure of sulfenamide and the reaction conditions, particularly the nature and concentration of the base, it is possible to control the orientation of animation.

LDA-promoted decomposition of benzenesulfenamides. A route to aminyl radicals by dioxygen oxidation of lithium amides

The LDA-promoted decomposition of N-monosubstituted sulfenamides 1a-d occurs through the formation of thioaminyl anions, which undergo oxidation either at sulfur, with formation of sulfonamides, or at nitrogen, with formation of thioaminyl radicals, depending on the nature of the 4'-substituent. The reaction of N,N-disubstituted sulfenamides 1e-h proceeds through the intermediacy of a lithium complex capable of generating aminyl radicals via sulfenyl group transfer to the di-iso-propylamido anion and subsequent aerial oxidation of the resulting lithium amides 3e-h.

SULFENAMIDES AND SULFINAMIDES VIII. THE CHROMATOGRAPHY OF ARYL SULFENAMIDES

Substituent effects with respect to position and extent of substitution in a series of N-aryl benzenesulfenamides (ArSNHAr') have been examined over several chromatographic systems.In normal phase TLC, although methyl substitution in either ring leads to