632358-70-4Relevant articles and documents
Rapid Bis-Coupling Reactivity with Triarylbismuth Reagents: Synthesis of Structurally Diverse Scaffolds and Step-economic Convergent Synthesis of Quebecol
Rao, Maddali L. N.,Murty, Venneti N.,Nand, Sachchida
, p. 1629 - 1636 (2020)
The cross-coupling study of gem-dibromoesters with triarylbismuths as threefold arylating reagents was investigated under palladium-catalyzed conditions. This study using triarylbismuth reagents explored the cross-coupling reactivity with various functionalized gem-dibromoesters. It furnished a variety of multi-functional trisubstituted acrylates embedded with aryl, alkene and alkyne scaffolds in high yields. The present study in turn, provided easy access to various triarylated acrylates and functionalized 1,3-dienyl and 1,3-enyne esters. Further, the established method applied in the step-economic and convergent synthesis of quebecol natural product in good yield.
Preparation method of α,β- or β,β-dihaloenones from diazodicarbonyls
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Paragraph 0031; 0036-0037; 0117-0118, (2017/08/30)
The present invention relates to a method for preparing andalpha;,andbeta;- or andbeta;,andbeta;-dihaloenone compounds from diazodicarbonyl compounds. According to the present invention, a diazo compound reacts with an oxalyl halide in the presence of a ruthenium catalyst so andalpha;,andbeta;- and andbeta;,andbeta;-dihaloenones can be synthesized through one-step reaction in an easy, simple and environmental manner. The synthesized andalpha;,andbeta;- and andbeta;,andbeta;-dihaloenones can be widely used for synthesis of intermediates of various drugs, natural materials, agricultural pesticides, dyes, etc. due to various biological activities.COPYRIGHT KIPO 2017
Preparation of 2,3,3-Triarylacrylic Acid Esters Using Suzuki-Miyaura Coupling Reactions
Cardinal, Sébastien,Voyer, Normand
, p. 1202 - 1216 (2016/05/11)
We report here a new strategy to produce 2,3,3-triarylacrylic acid esters, a class of 1,2,2-triarylethene compounds with an α,β-unsaturated ester functionality. Our approach requires the preparation of a gem-dibromoalkene precursor from an α-keto ester, followed by the installation of two aryl groups by Suzuki-Miyaura coupling reactions on the two C-Br bonds. Many 2,3,3-triarylacrylic acid esters with one, two, or three different aryl groups were obtained with complete regio- and stereocontrol in most cases.
Ruthenium(II)-catalyzed protocol for preparation of diverse α,β- and β,β-Dihaloenones from diazodicarbonyls
Magar, Krishna Bahadur Somai,Lee, Yong Rok
, p. 3422 - 3432 (2015/02/02)
Efficient one-step syntheses of α,β- and β,β-dihaloenones were achieved by ruthenium(II)- catalyzed reactions between cyclic or acyclic diazodicarbonyl compounds and oxalyl chloride or oxalyl bromide in moderate to good yields. This methodology offers sev
Stereoselective preparation of functionalized unsaturated lactones and esters via functionalized magnesium carbenoids
Vu, Viet Anh,Marek, Ilan,Knochel, Paul
, p. 1797 - 1802 (2007/10/03)
The reaction of β,β-dibromo or diiodo unsaturated esters with i-PrMgCl (1 equivalent) in diethyl ether allows the generation of functionalized alkenylmagnesium carbenoids which react with retention of configuration with various electrophiles providing polyfunctionalized unsaturated esters and lactones. By using two equivalents of i-PrMgCl, a 1,2-migration with retention of configuration occurs in diethyl ether allowing a new synthesis of tetrasubstituted esters and lactones.
