632365-25-4Relevant articles and documents
Discovery of 4H-pyrazolo[1,5-a]pyrimidin-7-ones as potent inhibitors of hepatitis C virus polymerase
Deng, Yongqi,Shipps Jr., Gerald W.,Wang, Tong,Popovici-Muller, Janeta,Rosner, Kristin E.,Siddiqui, M. Arshad,Duca, Jose,Cooper, Alan B.,Cable, Michael
, p. 5363 - 5367 (2009)
A series of 4H-pyrazolo[1,5-a]pyrimidin-7-one derivatives was synthesized and evaluated for inhibitory activity against HCV NS5B RNA-dependent RNA polymerase. A number of these compounds exhibited potent activity in enzymatic assay. The synthesis and stru