632365-95-8

Basic information

• Product Name: 2-Propen-1-one, 1-cyclohexyl-3-(dimethylamino)-2-[4-(phenylmethoxy)phenyl]-
• CAS NO: 632365-95-8
• Molecular Formula: C24H29NO2
• Molecular Weight: 363.5
• Mol File: 632365-95-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-cyclohexyl-3-(dimethylamino)-2-[4-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-cyclohexyl-3-(dimethylamino)-2-[4-(phenylmethoxy)phenyl]-(632365-95-8)
• EPA Substance Registry System: 2-Propen-1-one, 1-cyclohexyl-3-(dimethylamino)-2-[4-(phenylmethoxy)phenyl]-(632365-95-8)

Safety Data

• Hazardous Substances Data: 632365-95-8(Hazardous Substances Data)

Upstream product

• 632365-94-7 C₂₁H₂₄O₂ 
• 62393-45-7 methoxy bis(dimethylamino)methane 

Downstream Products

• 632362-06-2 6-(4-benzyloxy-phenyl)-7-cyclohexyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid methyl ester 
• 632362-08-4 6-(4-benzyloxy-phenyl)-7-cyclohexyl-pyrazolo[1,5-a]pyrimidine-3-carbonitrile 
• 632365-96-9 6-(4-benzyloxy-phenyl)-7-cyclohexyl-pyrazolo[1,5-a]pyrimidine 

Relevant articles and documents

Pyrazolo[1,5-a]pyrimidine-based inhibitors of HCV polymerase

The present paper describes a novel series of HCV RNA polymerase inhibitors based on a pyrazolo[1,5-a]pyrimidine scaffold bearing hydrophobic groups and an acidic functionality. Several compounds were optimized to low nanomolar potencies in a biochemical RdRp assay. SAR trends clearly reveal a stringent preference for a cyclohexyl group as one of the hydrophobes, and improved activities for carboxylic acid derivatives.