63237-80-9Relevant academic research and scientific papers
Synthesis of poly-substituted pyrazolo[1,5-a]quinolines through one-pot two component cascade reaction
Kato, Jun-Ya,Ijuin, Ryosuke,Aoyama, Hiroshi,Yokomatsu, Tsutomu
, p. 2766 - 2775 (2014/04/17)
A diversity-oriented method for the synthesis of novel poly-substituted pyrazolo[1,5-a]quinolines has been developed on the basis of an S NAr/Knoevenagel cyclization cascade reaction or an S NAr/Dieckmann-Thorpe cyclization cascade reaction. The methods provide a variety of poly-substituted pyrazolo[1,5-a]quinolines bearing an amino, alkyl or aryl substituent at the 5-position. In addition, a diversity-oriented method for the synthesis of 2-substituted pyrazolo[1,5-a]quinolines from a readily available 2-[[(trifluoromethyl) sulfonyl]oxy]pyrazolo[1,5-a]quinoline has also been disclosed.
Cycloaddition Reactions of N-p-Toluenesulfonylimino Derivatives of Quinoline and Isoquinoline. A Route to Pyrazoloquinolines and Pyrazoloisoquinolines
Sundberg, Richard J.,Ellis, James E.
, p. 573 - 576 (2007/10/02)
N-p-Toluenesulfonylimino ylides of quinoline and isoquinoline give cycloadducts with electrophilic acetylenes at 105 deg C.The adducts are spontaneously aromatized under the conditions of their formation by elimination of p-toluenesulfinic acid to give py
