56983-96-1

Usage

InChI:InChI=1/C17H12N2/c1-2-6-13(7-3-1)16-12-15-11-10-14-8-4-5-9-17(14)19(15)18-16/h1-12H

Upstream product

• 60230-81-1 4,5-dihydro-2-phenylpyrazolo<1,5-a>quinolin-3-carboxylic acid 
• 89876-88-0 2,4,6-Trimethyl-benzenesulfonate1-amino-2-phenylethynyl-quinolinium; 
• 70437-00-2 2-phenylethynylquinoline 
• 98-80-6 phenylboronic acid 
• 443891-21-2 2-bromoethynyl-quinoline 
• 218902-66-0 1,1-dibromo-2-(2-quinolyl)-1-ethene 
• 42599-24-6 E-styryl iodide 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 1531-38-0 2-benzoylmethylquinoline 
• 612-41-9 2-nitrocinnamic acid 
• 60230-80-0 ethyl 4,5-dihydro-2-phenylpyrazolo<1,5-a>quinolin-3-carboxylate 
• 94594-75-9 2-(2-Carboxy-ethyl)-benzenediazonium; chloride 
• 60230-79-7 (E)-3-(2-Oxo-3,4-dihydro-2H-quinolin-1-ylamino)-3-phenyl-acrylic acid ethyl ester 

Relevant academic research and scientific papers

HETERO-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME

The present invention provides: a heterocyclic compound which can significantly improve lifespan, efficiency, electrochemical stability, and thermal stability of an organic light emitting device; and an organic light emitting device containing the heterocyclic compound in an organic compound layer. The heterocyclic compound is represented by chemical formula 1.COPYRIGHT KIPO 2016

Synthesis of 2- and 2,3-substituted Pyrazolo[1,5- a ]pyridines: Scope and mechanistic considerations of a domino direct alkynylation and cyclization of n -iminopyridinium ylides using alkenyl bromides, alkenyl iodides, and alkynes

Direct functionalization and tandem processes have both received considerable recent interest due to their cost and time efficiency. Herein we report the synthesis of difficult to obtain 2-substituted pyrazolo[1,5-a] pyridines through a tandem palladium-catalyzed/silver-mediated elimination/direct functionalization/cyclization reaction involving N-benzoyliminopyridinium ylides. As such, these biologically important molecules are prepared in an efficient, high-yielding manner, only requiring a two-step sequence from pyridine. Aryl-substituted alkenyl bromides and iodides are effective ylide coupling partners. Mechanistic studies led to the use of terminal alkynes, which extended the scope of the reaction to include alkyl substitution on the unsaturated reactive site. The optimization, scope, and mechanistic considerations of the process are discussed.

Synthesis of 2-Substituted Pyrazolo[1,5-a]pyridines through Cascade Direct Alkenylation/Cyclization Reactions

[Chemical equation presented] The synthesis of 2-substituted pyrazolo[1,5-a]pyridines from N-iminopyridinium ylides is described. These medicinally interesting compounds are formed through a cascade process involving a palladium-catalyzed direct alkenylation reaction followed by silver-mediated cyclization. The reaction can be performed with a wide range of electron-poor and electron-rich alkenyl iodides in good yields. This work represents perhaps the most direct route for the preparation of these compounds.

Synthesis and pregnancy terminating activity of pyrazolo[1,5-a]indoles and quinolines

In order to clarify the structural requirements for antifertility activity, series of 2-arylpyrazolo[1,5-a]indoles and 2-arylpyrazolo[1,5-a]-quinolines were prepared and tested in rats and hamsters. Their potencies were compared with those of the isomeric

Thermal Rearrangements of Cyclic Amine Ylides. III. Intramolecular Cyclization of 2-Ethynylpyridine N-Imides to 3-Azaindolizine Derivatives

Treatment of the N-aminopyridinium salts (5a-e) prepared from 2-ethynylpyridines (4) with potassium carbonate resulted in an intramolecular cyclization to give the corresponding 3-azaindolizines (6) (pyrazolopyridines), presumably via the ionic in

Cycloaddition Reactions of N-p-Toluenesulfonylimino Derivatives of Quinoline and Isoquinoline. A Route to Pyrazoloquinolines and Pyrazoloisoquinolines

N-p-Toluenesulfonylimino ylides of quinoline and isoquinoline give cycloadducts with electrophilic acetylenes at 105 deg C.The adducts are spontaneously aromatized under the conditions of their formation by elimination of p-toluenesulfinic acid to give py

Ring Closures of syn-(E)- and anti-(E)-(2-Quinolylmethyl)- and -(1-Isoquinolylmethyl)ketoximes to Pyrazoloquinolines and Pyrazoloisoquinolines

The (2-quinolylmethyl)- and (1-isoquinolylmethyl)ketoximes 2a-e and 4a-d have been prepared and the oxime configurations determined.The Pyrazoloquinolines 7a, b and the pyrazoloisoquinoline 8a are formed by Beckmann reaction of the anti-isomers 2a, b and 4a, while O-mesitylsulfonylhydroxylamine yields the pyrazolo compounds 7 and 8, independent of the oxime configuration.

Rearrangement of 2-Ethynylpyridinium N-Imides to Pyrazolopyridines

Pyrazolopyridines (6) are obtained from the N-amino-2-ethynylpyridinium salts (5) on treatment with base.

2-Phenyl-pyrazolo-[1,5-a]quinoline compounds

New heterocyclic compounds represented by the following formula: STR1 wherein: R and R1 are independently selected from hydrogen, hydroxy, (C1-4)alkyl, (C1-4)alkoxy, (C3-5)alkenyloxy, (C3-5)alkynyloxy