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6324-50-1 Usage

General Description

2,4,6-Trichloroiodobenzene, also known as TCI, is a chlorinated iodobenzene compound with the chemical formula C6H2Cl3I. It is a highly reactive chemical compound that is primarily used in the field of organic synthesis as a reagent for various reactions, such as cross-coupling reactions and nucleophilic substitution reactions. TCI is a toxic and potentially hazardous compound that requires careful handling and storage. It is also used as an intermediate in the production of pharmaceuticals and agrochemicals, as well as in the manufacture of dyes and other specialty chemicals. Additionally, TCI is known for its potential environmental impact, as it is considered a persistent organic pollutant and is subject to regulations and restrictions in many countries.

Check Digit Verification of cas no

The CAS Registry Mumber 6324-50-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,2 and 4 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6324-50:
81 % 10 = 1
So 6324-50-1 is a valid CAS Registry Number.

6324-50-1 Well-known Company Product Price

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  • Alfa Aesar

  • (L11975)  1,3,5-Trichloro-2-iodobenzene, 96%   

  • 6324-50-1

  • 1g

  • 462.0CNY

  • Detail
  • Alfa Aesar

  • (L11975)  1,3,5-Trichloro-2-iodobenzene, 96%   

  • 6324-50-1

  • 5g

  • 1652.0CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017


1.1 GHS Product identifier

Product name 2,4,6-Trichloroiodobenzene

1.2 Other means of identification

Product number -
Other names 2,4,6-Trichloro-1-iodobenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6324-50-1 SDS

6324-50-1Relevant articles and documents

Late stage iodination of biologically active agents using a one-pot process from aryl amines

Sloan, Nikki L.,Luthra, Sajinder K.,McRobbie, Graeme,Pimlott, Sally L.,Sutherland, Andrew

, p. 54881 - 54891 (2017/12/12)

A simple and effective one-pot tandem procedure that generates aryl iodides from readily available aryl amines via stable diazonium salts has been developed. The operationally simple procedure and mild conditions allow late-stage iodination of a wide range of aryl compounds bearing various functional groups and substitution patterns. A novel synthetic strategy involving the preparation of nitroaryl compounds followed by a chemoselective tin(ii) dichloride reduction and the use of the one-pot diazotisation-iodination transformation was also developed. The general applicability of this approach was demonstrated with the preparation of a number of medicinally important compounds including CNS1261, a SPECT imaging agent of the N-methyl-d-aspartate (NMDA) receptor and IBOX, a compound used to detect amyloid plaques in the brain.



Paragraph 0126-0128, (2013/03/28)

Compounds of Formula (I) wherein R1 is C1-C4alkyl or C1-C4 haloalkyl; R2 is C1-C4alkyl; R3 is hydrogen or halogen; R4 is hydrogen, C1-C4alkyl or C1-C4halogenalkyl; R5 is hydrogen, halogen, C1-C4alkyl or C1-C4halogenalkyl; R6 is hydrogen, halogen, C1-C4alkyl, C2-C6alkenyl or C3-C6alkinyl; R7 is hydrogen, halogen, C1-C6alkyl, C2-C6alkenyl, C3-C6alkinyl, C3-C6cycloalkyl-C3-C6alkinyl, halophenoxy, halophenyi, C1-C6haloalkyl, C1-C6haloakoxy, C2-C6haloalkenyl, or C2-C6haloalkenyloxy; R8 is hydrogen, halogen, C1-C4alkyl, C2-C6alkenyl or C3-C6alkinyl; with the provisio that at least one of R6, R7 and R8 is different from hydrogen; n is 0 or 1, are suitable for use as microbriocides.

Iodination of aryl amines in a water-paste form via stable aryl diazonium tosylates

Gorlushko, Dmitry A.,Filimonov, Victor D.,Krasnokutskaya, Elena A.,Semenischeva, Nadya I.,Go, Bong Seong,Hwang, Ho Yun,Cha, Eun Hye,Chi, Ki-Whan

, p. 1080 - 1082 (2008/09/18)

The diazotization of aryl amines at room temperature in paste form with NaNO2, p-TsOH and a small amount of water, followed by treatment with KI provides a new, simple, and effective route for the preparation of various aryl iodides. The water-paste and strong acid-free reaction conditions are environmentally friendly and compatible with acid-sensitive functional groups.

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