63262-66-8Relevant articles and documents
THE ANOMERIC EFFECT OF THE CARBOETHOXY GROUP IN OXYGEN AND SULPHUR CONTAINING HETEROCYCLES
Taschierske, C.,Koehler, H.,Zaschke, H.,Kleinpeter, E.
, p. 6987 - 6998 (1989)
The anomeric effect of the carboethoxy substituents and the ring oxygen in 1,3-dioxane- and 1,3-oxathiane-2-carboxylates has been estimated in low polar solvents by including empirical correlation factor α to be 4 kJ/mol.The conformational energies of the
HETEROARYL RHEB INHIBITORS AND USES THEREOF
-
Paragraph 00700, (2018/11/10)
The present invention provides compounds, compositions thereof, and methods of using the same. Compositions comprising a compound of this invention or a pharmaceutically acceptable derivative thereof and a pharmaceutically acceptable carrier, adjuvant, or vehicle. The amount of the compound in compositions of this invention is such that it is effective to measurably inhibit Rheb, in a biological sample or in a patient.
BIARYL PYRAZOLES AS NRF2 REGULATORS
-
, (2017/08/01)
The present invention relates to biaryl pyrazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.