632626-22-3Relevant academic research and scientific papers
Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists
Hall, Adrian,Atkinson, Stephen,Brown, Susan H.,Chessell, Iain P.,Chowdhury, Anita,Giblin, Gerard M.P.,Goldsmith, Paul,Healy, Mark P.,Jandu, Karamjit S.,Johnson, Matthew R.,Michel, Anton D.,Naylor, Alan,Sweeting, Jennifer A.
, p. 1200 - 1205 (2007/10/03)
Replacement of the carboxylic acid group in a series of previously described 1,5-biaryl pyrrole EP1 receptor antagonists led to the discovery of various novel non-acidic antagonists. Several analogues displayed high binding affinity and high bi
