6328-01-4

Usage

Uses

Used in Fragrance Industry:
ETHYL 3-AMINOCINNAMATE is used as a fragrance ingredient for its sweet, floral scent, enhancing the olfactory appeal of perfumes and other scented products.
Used in Cosmetic Industry:
ETHYL 3-AMINOCINNAMATE is used as a scent additive in lotions and other beauty products to provide a pleasant aroma, improving the sensory experience for users.
Used in Therapeutic Applications:
ETHYL 3-AMINOCINNAMATE is studied for its potential use as a protective agent against ultraviolet radiation, suggesting its possible application in sunscreens and other protective skincare products.
ETHYL 3-AMINOCINNAMATE is also researched for its anti-inflammatory properties, indicating a potential role in treatments for inflammatory conditions or as a component in anti-inflammatory formulations.
It is important to highlight that due to its potential to cause skin irritation, ETHYL 3-AMINOCINNAMATE should be used with caution and in accordance with safety guidelines to prevent adverse effects.

InChI:InChI=1/C11H13NO2/c1-2-14-11(13)7-6-9-4-3-5-10(12)8-9/h3-8H,2,12H2,1H3/b7-6+

Upstream product

• 64-17-5 ethanol 
• 1664-56-8 m-aminocinnamic acid 
• 5396-71-4 ethyl 3-(3-nitrophenyl)acrylate 
• 626-01-7 3-Iodoaniline 
• 140-88-5 ethyl acrylate 

Downstream Products

• 122195-55-5 N-(m-phenyl)-N'-(diethylaminothiocarbonyl)benzamidin 
• 130750-32-2 (Z)-3-[3-({[(Z)-Morpholine-4-carbothioylimino]-phenyl-methyl}-amino)-phenyl]-acrylic acid ethyl ester 
• 925705-58-4 3-{3-[(dibenzofuran-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl ester 
• 925705-53-9 3-{3-[(5-phenoxy-furan-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl ester 

Relevant academic research and scientific papers

Histone deacetylase inhibitors and its preparation method and use thereof

The invention discloses a histone deacetylase inhibitor and its preparation method and use, the invention discloses a compound of the formula I as shown, or its crystalline form, or its pharmaceutically acceptable salt, or solvate thereof, or prodrug thereof, or its metabolic product. The invention of the formula I illustrated new compound, has shown good deacetylase inhibition activity, with the histone deacetylase for clinical treatment of diseases associated with abnormal activity of a new pharmaceutical may be.

Recycled Pd/C-Catalyzed Heck Reaction of 2-Iodoanilines under Ligand-Free Conditions

Recyclable Pd/C-catalyzed Heck reaction of 2-iodoanilines with acrylate has been developed. The reaction occurred readily in 1,4-dioxane using Pd/C (10 wt%) as catalyst under ligand-free conditions, and the cross-coupling products were obtained with medium to high yield. Gram-scale reactions and recycling of the catalyst were also demonstrated.

EP2 RECEPTOR AGONISTS

A compound of formula (III): or a salt, solvate and chemically protected form thereof, wherein: R5 is an optionally substituted C5-20 aryl or C4-20alkyl group; L′ is a single bond, —O— or —C(═O)—; A is selected from the group consisting of: formulae (i) (ii) (iii) wherein X and Y are selected from the group consisting of: O and CR3; S and CR3; NH and CR3; NH and N; O and N; S and N; N and S; and N and O, and where the dotted lines indicate a double bond in the appropriate location, and where Q is either N or CH; D is selected from: formulae (i) (ii) (iii) (iv) (v) (vii) (viii) (ix) B is selected from the group consisting of: formulae (A) (B) where RP6 is selected from fluoro and chloro; and R2 is either: (i) —CO2H; (ii) —CONH2; (iii) —CH2—OH; or (iv) tetrazol-5-yl.