63296-17-3Relevant articles and documents
Disproportionation reaction of disulfides promoted by nitric oxide (NO) in the presence of oxygen
Itoh, Takashi,Tsutsumi, Nozomi,Ohsawa, Akio
, p. 2161 - 2166 (1999)
Two disulfides brought about disproportionation reaction to afford an unsymmetrical disulfide in 50% yield with a catalytic amount of nitric oxide in the presence of oxygen. The reaction proceeded faster when alkyl disulfides were employed for the reaction, and the substituent effects suggested that the reaction commenced with an oxidative process.
PdCl2/DMSO-Catalyzed Thiol-Disulfide Exchange: Synthesis of Unsymmetrical Disulfide
Guo, Jimin,Zha, Jianjian,Zhang, Tao,Ding, Chang-Hua,Tan, Qitao,Xu, Bin
supporting information, p. 3167 - 3172 (2021/05/05)
Unsymmetrical disulfides have been effectively prepared through thiol exchange with symmetrical disulfides employing a simple PdCl2/DMSO catalytic system. The given method features excellent functional group tolerance, a broad substrate scope, and operational simplicity. This reaction is especially useful for late-stage functionalization of bioactive scaffolds such as peptides and pharmaceuticals. Disulfide-containing organic dyes have also been prepared. This transformation could be extended to thiol-diselenide or thiol-ditelluride exchange affording RS-SeR′ or RS-TeR′.
Method for NFSI-catalyzed synthesis of asymmetric disulphide derivatives
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Paragraph 0018-0025, (2021/10/30)
The invention belongs to the field of fine chemical engineering, and relates to a method for NFSI-catalytically synthesizing an asymmetric disulphide derivative, which comprises the following steps: NFSI. The symmetric disulfide A and the symmetric disulf